Breast Cancer and Nutrition: A Paradigm for Prevention in 3D Across the Life Course

Frontiers in Oncology
Michele R Forman

Abstract

Breast cancer, the most common cancer in women worldwide, has recognized reproductive and anthropometric risk factors including age at menarche and adult height. Yet the age when a woman attains her adult height or experiences menarche for example is simply the timing of the major life event at the end of a long trail of exposures that began in utero. The objective of this article is to investigate through a review of the literature the role of nutrition in breast cancer prevention through three dimensions (D). Each D offers a different lens. The First D identifies windows/ages of exposures or conditions that convey vulnerability or protection from breast cancer. The Second D addresses the intensity and duration of the exposure; and the (Third D) examines the pace, i.e., how rapid or slow the young woman experiences her growth and development. Birthweight illustrative of the First D reveals a strong signal across the life course on BC risk, but the risk group varies from low to high birthweight. Stressful life events like being a pubertal aged girl living in a household with an unemployed father during the Great Depression or high levels of environmental contaminants exposure are representative of the Second D. Height velocity ...Continue Reading

References

Sep 1, 1988·British Journal of Cancer·L BernsteinB E Henderson
Jan 1, 1993·Epidemiologic Reviews·J L Kelsey
Jan 1, 1993·Epidemiologic Reviews·J L KelseyE M John
Oct 1, 1996·Annals of Internal Medicine·B R OlsonB Güttsches-Ebeling
Oct 1, 1996·The American Journal of Clinical Nutrition·M R FormanB I Graubard
Sep 1, 1996·Cancer Causes & Control : CCC·J A RossS M Davies
Mar 5, 2002·British Journal of Cancer·C A HaimanL Shames
Oct 16, 2004·The New England Journal of Medicine·Martin AhlgrenThorkild I A Sørensen
Nov 25, 2005·Cancer Investigation·Michele R FormanYawei Zhang
Jun 17, 2006·Carcinogenesis·Karin B MichelsWalter C Willett
Jul 11, 2006·International Journal of Cancer. Journal International Du Cancer·Heather J BaerKarin B Michels
Oct 13, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Veronica Wendy SetiawanBrian E Henderson
Oct 13, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Christopher I LiEmily White
Oct 17, 2007·Environmental Health Perspectives·Barbara A CohnRobert I Sholtz
Jul 28, 2009·Journal of Women's Health·Xiaohui XuJeffrey Roth
Dec 17, 2014·Reproductive Toxicology·Jeremy Michals SchrawMichele R Forman
Nov 20, 2015·Breast Cancer Research and Treatment·Catherine S BerkeyGraham A Colditz
Jul 29, 2016·International Journal of Epidemiology·Fei XueKarin B Michels
Dec 13, 2016·Pediatrics·Karin B MichelsMary Beth Terry
Jan 31, 2017·International Journal of Cancer. Journal International Du Cancer·Bernard RosnerGraham A Colditz
Jun 23, 2018·JAMA Oncology·UNKNOWN Premenopausal Breast Cancer Collaborative GroupAnthony J Swerdlow
Sep 27, 2018·International Journal of Cancer. Journal International Du Cancer·Rachel J J ElandsMatty P Weijenberg
Oct 9, 2018·Cancer·Rowan T ChlebowskiMarcia L Stefanick
May 21, 2019·American Journal of Epidemiology·Mandy GoldbergMary Beth Terry
Oct 5, 2019·International Journal of Cancer. Journal International Du Cancer·Juhua LuoMichael Hendryx

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