PMID: 16522978Mar 9, 2006Paper

Breast cancer and scleroderma

Skinmed
Alon ScopeMicahel Ehrenfeld

Abstract

Epidemiologic studies have shown that patients with scleroderma have an increased risk of cancer. The authors report eight cases and retrospectively review the published data on the possible association between breast cancer and scleroderma of the cutaneous and systemic forms. The records of all patients with scleroderma and breast cancer who were hospitalized during 1980-2002 in the Chaim Sheba Medical Center were surveyed. A literature search for breast cancer and scleroderma was performed. The clinical data of 65 women patients with breast cancer and scleroderma, eight of whom were hospitalized in the Chaim Sheba Medical Center and 57 who were reported in the literature, are summarized. In 29 patients (44%), scleroderma appeared before or simultaneously with the diagnosis of breast cancer. While a higher frequency of systemic scleroderma was described in this group, a higher rate of cutaneous scleroderma appeared in the group where scleroderma followed breast cancer diagnosis (p<0.001). Large-scale case-control studies are needed to substantiate the possible association between scleroderma-both cutaneous and systemic-and breast cancer.

References

Jun 1, 1979·The Journal of Experimental Medicine·M B KahalehE C LeRoy
Apr 1, 1979·Annals of the Rheumatic Diseases·P C Mattingly, A G Mowat
Feb 1, 1990·The Biochemical Journal·G A MurrellL Bromley
Feb 1, 1989·British Journal of Rheumatology·A M ForbesR M Graham
Aug 1, 1989·British Journal of Rheumatology·G Papasavvas, C J Goodwill
Jun 1, 1989·The British Journal of Dermatology·G B ColverJ A Hunter
Oct 1, 1989·International Journal of Radiation Oncology, Biology, Physics·R FleckF A Holmes
Feb 1, 1988·Postgraduate Medical Journal·A J BarnettG O Littlejohn
Dec 1, 1985·Arthritis and Rheumatism·A D Roumm, T A Medsger
Apr 1, 1993·Arthritis and Rheumatism·M Abu-ShakraP Lee
Sep 1, 1995·Cancer·A K RosenthalO Nyrén
May 16, 1998·The Journal of Pathology·S A CottonA J Freemont
May 26, 1998·Annals of Plastic Surgery·D ChauM T Longaker
Dec 16, 1998·British Journal of Plastic Surgery·D HuG W Cherry
May 20, 1999·The Australasian Journal of Dermatology·N R BleaselV A Ahern
Feb 22, 2000·Dermatology : International Journal for Clinical and Investigative Dermatology·J V SchafferM Girardi
Feb 25, 2000·Journal of the American Academy of Dermatology·T KonoS Taniguchi
Apr 2, 2002·The Journal of Surgical Research·M Ann KuhnMartin C Robson
May 8, 2002·Pediatric Dermatology·Uwe WollinaWolfgang Weyers
Feb 13, 2003·Journal of the American Academy of Dermatology·I KupferP Joly
Jul 9, 2003·Cancer Causes & Control : CCC·Siegal SadetzkiMoshe Z Papa

❮ Previous
Next ❯

Citations

Feb 19, 2008·Rheumatology International·Tim Y-T LuPeter J Roberts-Thomson
Aug 10, 2011·Current Opinion in Rheumatology·Ami A Shah, Antony Rosen
Sep 22, 2010·The British Journal of Dermatology·A B OlesenH T Sørensen
Oct 28, 2014·International Journal of Rheumatic Diseases·Santoshkumar MandalDebashish Danda
Dec 14, 2011·Scandinavian Journal of Rheumatology·C-F KuoL-C See
Aug 26, 2011·Dermatology : International Journal for Clinical and Investigative Dermatology·B LaetschS Lautenschlager
Apr 28, 2007·The Breast Journal·Geeta ShettySteven Thrush
Dec 22, 2007·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Jeffery H WoottonChris J Diederich
Jan 8, 2008·Southern Medical Journal·Marc Wooten

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.