Breast cancer: gadolinium-enhanced MR imaging with a 0.5-T open imager and three-point Dixon technique

Radiology
B L DanielR J Herfkens

Abstract

To investigate the three-point Dixon technique as a method for obtaining fat-nulled images of contrast material-enhancing breast lesions with a 0.5-T open magnetic resonance (MR) imager. Real and imaginary source images were obtained with an interleaved gradient-echo sequence with a repetition time of 550 msec and echo times of 12.8, 19.8, and 26.8 msec. Twenty-four to 28 sections were obtained in the sagittal plane with a 90 degrees flip angle, 256 x 192 matrix, 3-4.5-mm section thickness, and acquisition time of 10 minutes 54 seconds. A three-point Dixon reconstruction algorithm was used to generate water-specific, fat-specific, and combined images from the raw image data. Twelve breasts in 10 patients and one healthy volunteer were imaged. Three-point Dixon images were superior to extended two-point Dixon and fat-suppressed images and to images generated by means of subtraction of three-dimensional fast spoiled gradient-echo images obtained before contrast material injection from those obtained after. Three-point Dixon imaging provides a robust method for creating fat-nulled images of enhancing breast lesions in the 0.5-T open MR environment. Water-specific three-point Dixon images are successful in regions of B0 heterogenei...Continue Reading

Citations

May 10, 2006·European Radiology·M A A J van den BoschD M Ikeda
Sep 28, 2010·Radiologic Clinics of North America·Susan Weinstein, Mark Rosen
Sep 26, 2003·Journal of Magnetic Resonance Imaging : JMRI·Milica MedvedGregory S Karczmar
Oct 13, 2006·Journal of Magnetic Resonance Imaging : JMRI·Glen R Morrell
Apr 8, 2010·Journal of Magnetic Resonance Imaging : JMRI·Huong Le-PetrossJingfei Ma
Sep 13, 2006·International Journal of Radiation Oncology, Biology, Physics·Billy W LooQuynh-Thu Le
Aug 9, 2005·Magnetic Resonance Imaging Clinics of North America·Maurice A A J van den Bosch, Bruce L Daniel
Nov 10, 2001·Annual Review of Biomedical Engineering·J KettenbachF A Jolesz
Dec 4, 2003·Technology in Cancer Research & Treatment·S MerrittO Nalcioglu
Aug 26, 2004·The Breast Journal·Regina S OffodileDebra M Ikeda
Jan 6, 2001·Topics in Magnetic Resonance Imaging : TMRI·B L Daniel

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