Breast cancer in adolescents and young adults

Pediatric Blood & Cancer
Rebecca H JohnsonArchie Bleyer

Abstract

Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable biological characteristics, distant metastatic disease at diagnosis, and adverse outcome. Endocrine therapy and some chemotherapy recommendations differ between young and older women. AYAs require coordinated multidisciplinary care, treatment regimens that minimize late effects such as premature menopause and osteoporosis, and proactive management of psychological and sexual health during and after cancer treatment.

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Citations

Apr 23, 2019·Journal of Oncology Practice·Peter F Coccia
Nov 26, 2019·Journal of Adolescent and Young Adult Oncology·Danny R YouldenJoanne F Aitken
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Apr 6, 2021·World Journal of Biological Chemistry·Rama Rao MallaGanji Purnachandra Nagaraju
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