Breast Cancer in Canadian Women

BMC Women's Health
Heather Bryant

Abstract

HEALTH ISSUE: Although lung cancer is the leading cause of cancer deaths for Canadian women, breast cancer is the most frequently diagnosed. About 5400 women are expected to die from this disease in 2003. In 1998, a woman's lifetime risk of breast cancer was about one in nine. KEY FINDINGS: A number of risk factors for breast cancer have been identified. These include advancing age, hormonal factors (eg. early menarche, late menopause and late age at first full-term pregnancy), familial risk, BRCA-1 and BRCA-2 gene mutations, diet and postmenopausal obesity.Several interventions have been introduced to assist women at high risk for breast cancer, including genetic counseling and testing for women who have strong family histories of breast cancer; selective estrogen receptor modifiers, such as tamoxifen, that has been shown to reduce breast cancer rates; prophylactic mastectomy and screening. DATA GAPS AND RECOMMENDATIONS: Guidelines are unclear in several areas, particularly in screening. Where clinical guidelines are available, health services research or ongoing monitoring (by provincial/territorial cancer agencies) is needed to assess compliance with the guidelines and to ensure equity of access within the provinces/territor...Continue Reading

References

May 7, 1987·The New England Journal of Medicine·W C WillettF E Speizer
Aug 2, 1995·Journal of the National Cancer Institute·E V Kliewer, K R Smith
Jun 8, 1995·The New England Journal of Medicine·H Bryant, P Brasher
Oct 20, 1993·Journal of the National Cancer Institute·S W FletcherS Shapiro
Jan 1, 1996·Annual Review of Public Health·J L Kelsey, L Bernstein
Jan 1, 1996·Acta Oncologica·A B Miller, L A Gaudette
Nov 6, 1996·Journal of the National Cancer Institute·K C ChuB K Edwards
Feb 5, 1997·Journal of the National Cancer Institute·R E TaroneL A Gaudette
Oct 6, 1997·AJR. American Journal of Roentgenology·R Ballard-BarbashL G Kessler
Apr 17, 1998·The New England Journal of Medicine·J G ElmoreS W Fletcher
Oct 28, 1998·Journal of the National Cancer Institute·S M LippmanA L Sabichi
Mar 31, 1999·International Journal of Radiation Oncology, Biology, Physics·L F PaszatE Holowaty
May 18, 1999·Journal of the National Cancer Institute·T Reynolds
Jun 8, 1999·American Journal of Public Health·C E De GrasseK Breithaupt
Aug 13, 1999·Breast Cancer Research and Treatment·T LeivoO P Heinonen
Oct 31, 2001·Lancet·O Olsen, P C Gøtzsche
Nov 8, 2001·Journal of the National Cancer Institute·L C HartmannR B Jenkins
Nov 22, 2001·Journal of the National Cancer Institute·J T HartmannC Bokemeyer
Dec 18, 2001·American Journal of Epidemiology·P TerryA Wolk
Feb 19, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·P T KatzmarzykC Bouchard
Feb 22, 2002·British Journal of Cancer·A C AntoniouD F Easton
Mar 23, 2002·BMJ : British Medical Journal·Zosia Kmietowicz
Jul 19, 2002·JAMA : the Journal of the American Medical Association·Jacques E RossouwUNKNOWN Writing Group for the Women's Health Initiative Investigators
Nov 20, 2004·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J S Tobias
Jul 10, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Larry F EllisonLeslie S Mery
Aug 1, 1923·American Journal of Public Health : the Journal of the American Public Health Association·M Nicoll

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Citations

Oct 10, 2006·International Journal for Equity in Health·Moyra E BrackleyMary L Lesperance
Dec 21, 2006·International Journal of Health Services : Planning, Administration, Evaluation·Dennis Raphael

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