Breast cancer-related lymphedema: risk factors, precautionary measures, and treatments

Gland Surgery
Tessa C GillespieAlphonse G Taghian

Abstract

Breast cancer-related lymphedema (BCRL) is a negative sequela of breast cancer treatment, and well-established risk factors include axillary lymph node dissection (ALND) and regional lymph node radiation (RLNR). BCRL affects approximately 1 in 5 patients treated for breast cancer, and it has a significant negative impact on patients' quality of life after breast cancer treatment, serving as a reminder of previous illness. This paper is a comprehensive review of the current evidence regarding BCRL risk factors, precautionary guidelines, prospective screening, early intervention, and surgical and non-surgical treatment techniques. Through establishing evidence-based BCRL risk factors, researchers and clinicians are better able to prevent, anticipate, and provide early intervention for BCRL. Clinicians can identify patients at high risk and utilize prospective screening programs, which incorporate objective measurements, patient reported outcome measures (PROM), and clinical examination, thereby creating opportunities for early intervention and, accordingly, improving BCRL prognosis. Innovative surgical techniques that minimize and/or prophylactically correct lymphatic disruption, such as axillary reverse mapping (ARM) and lymphat...Continue Reading

Citations

Feb 28, 2019·British Journal of Nursing : BJN·Mary Woods
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Sep 25, 2019·Nature Reviews. Disease Primers·Nadia HarbeckFatima Cardoso
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Mar 12, 2019·Annals of Plastic Surgery·Anna Rose JohnsonDhruv Singhal
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