Abstract
An increasing number of studies indicates that the strength and even direction of association between breast cancer and established risk factors differ according to the woman's age when she develops the disease. This was studied in the setting of a population based cancer registry using a databank with information on age at menarche, parity, age at first birth, oral contraceptive (OC) use, lactation, height and weight. From a cohort of 80.219 women attending population-based cervical and breast cancer screening in Iceland, 1120 cases were identified, aged 26-90 years at diagnosis and 10,537 controls, individually matched to the cases on birth year and age when attending. Information given at last visit before diagnosis was used in the analysis, applying conditional logistic regression. Odds ratios and statistical strength of relationships varied according to age at diagnosis for age at first birth, number of births, duration of lactation, height and weight. The decreased risk associated with young age at first birth and increasing duration of breast feeding became less pronounced with advancing age at diagnosis. A reduced risk associated with an increasing number of births was not detected in women diagnosed under the age of 40...Continue Reading
References
Jun 15, 1978·International Journal of Cancer. Journal International Du Cancer·H TuliniusM Gonzales
Jan 1, 1992·Breast Cancer Research and Treatment·J RussoI H Russo
Mar 15, 1992·Cancer·H T LynchJ F Lynch
Mar 1, 1992·Journal of Medical Genetics·H TuliniusL Tryggvadóttir
Jan 1, 1992·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·L J Vatten, S Kvinnsland
Jul 1, 1991·Epidemiology·E Lund
Mar 3, 1990·BMJ : British Medical Journal·E M WilliamsK McPherson
Dec 15, 1990·International Journal of Cancer. Journal International Du Cancer·H TuliniusK Sigurösson
Oct 29, 1988·BMJ : British Medical Journal·P BruzziM R Del Turco
Feb 15, 1986·International Journal of Cancer. Journal International Du Cancer·A B Miller, R D Bulbrook
Jan 1, 1982·Breast Cancer Research and Treatment·J RussoI H Russo
Nov 1, 1982·American Journal of Epidemiology·D T Janerich, M B Hoff
Jul 1, 1995·Cancer Causes & Control : CCC·D A LeonM F Murphy
Aug 1, 1995·British Journal of Cancer·G AlbrektsenG Kvåle
Mar 1, 1995·Epidemiology·G UrsinS Greenland
Jan 2, 1993·Lancet·W R Miller
Apr 24, 1993·Lancet·V Beral, G Reeves
Mar 1, 1994·Annals of Human Biology·L TryggvadóttirM Lárusdóttir
Jul 7, 1994·The New England Journal of Medicine·M LambeH O Adami
Jan 1, 1993·Epidemiologic Reviews·D J Hunter, W C Willett
Jan 1, 1993·Epidemiologic Reviews·J L Kelsey
Jan 1, 1993·Epidemiologic Reviews·J L KelseyE M John
May 1, 1996·Nature Genetics·S ThorlaciusJ E Eyfjörd
Jan 1, 1997·British Journal of Cancer·L TryggvadóttirG B Gudmundsdóttir
Apr 16, 1998·International Journal of Cancer. Journal International Du Cancer·M McCredieS Williams
May 13, 1998·Cancer Causes & Control : CCC·M R McCredieJ L Hopper
Nov 5, 1998·Lancet·O JohannssonH Olsson
Dec 16, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S ColdC Rose
Jun 8, 1999·Journal of the National Cancer Institute·J PetoM R Stratton
Dec 10, 1999·Lancet·H JernströmS A Narod
Jun 24, 2000·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·F de Waard
Sep 21, 2000·American Journal of Epidemiology·P A van den BrandtD J Hunter
Jun 28, 2001·American Journal of Epidemiology·L TryggvadóttirT Sigurvinsson
Citations
Sep 24, 2004·International Journal of Cancer. Journal International Du Cancer·Kee-Seng ChiaBenjamin Mow
Aug 1, 2013·Breast Cancer Research and Treatment·Seokang ChungDaehee Kang
Jun 1, 2006·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Luisa N BorrellMary Beth Terry
Oct 18, 2002·Lancet·Irma H Russo
Apr 20, 2006·Journal of the National Cancer Institute·Nadine AndrieuUNKNOWN IBCCS Collaborators Group
Sep 14, 2004·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·G C ZografosN Panou
Jan 15, 2005·Cancer Science·Koji TamakoshiUNKNOWN JACC Study Group
Jul 25, 2013·BMC Family Practice·Imran RafiSimon de Lusignan
Aug 21, 2003·Breast Cancer Research : BCR·Laufey TryggvadottirJorunn E Eyfjord
Dec 15, 2010·The Oncologist·Jennifer K Litton, Richard L Theriault
May 2, 2012·Annals of Internal Medicine·Heidi D NelsonDiana L Miglioretti
Mar 24, 2005·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·B MøllerT Haldorsen
Sep 17, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·K KjaerheimE Pukkala
Feb 6, 2007·The Breast : Official Journal of the European Society of Mastology·I PappoA Halevy
Dec 24, 2004·Surgical Oncology·Jean AdamsDavid Forman
Mar 7, 2015·Breast Cancer Research and Treatment·Laureen DartoisGuy Fagherazzi
Aug 6, 2002·BMC Women's Health·Elina HemminkiTimo Hakulinen
Dec 7, 2010·Aesthetic Surgery Journal·Safa E SharabiS Eva Singletary
Sep 19, 2014·The Breast : Official Journal of the European Society of Mastology·Soley BayraktarBanu Arun
Nov 21, 2009·Acta Oncologica·Eero PukkalaKristina Kjaerheim
May 19, 2017·American Journal of Epidemiology·Hyun Ja KimEunyoung Cho
May 25, 2006·International Journal of Cancer. Journal International Du Cancer·Jolanta LissowskaMontserrat García-Closas
Aug 22, 2007·International Journal of Cancer. Journal International Du Cancer·Shehnaz K HussainKari Hemminki
Nov 23, 2019·International Journal of Cancer. Journal International Du Cancer·Hwayoung NohIsabelle Soerjomataram
Jan 25, 2003·Current Opinion in Obstetrics & Gynecology·Cecile T M Brekelmans
Oct 24, 2006·The Journal of Nutrition·Teresa González-CossíoJaime Sepúlveda
Feb 20, 2020·Breast Cancer Research and Treatment·Lili ChenChuan Wang
Aug 29, 2018·Cancer Causes & Control : CCC·Sushmita KatuwalEero Pukkala
Sep 10, 2013·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Jennifer M GierischEvan R Myers