Breast carcinoma with numerous large "thanatosomes"

Journal of Cancer Research and Therapeutics
N K PanickerAnand R Patel

Abstract

Intracytoplasmic and stromal eosinophilic hyaline globules (HGs) have been observed in various neoplastic and nonneoplastic conditions. Thanatosomes are also such HGs seen invariably associated with increased apoptosis and may contain nuclear fragments, occasionally observed in high-grade tumors. We are reporting a case of high-grade breast carcinoma with this striking morphological feature. Their probable nature, pathogenesis, and significance are discussed with review of literature.

Citations

Dec 9, 2015·Biomarkers in Medicine·Lucilla ParnettiDavide Chiasserini
Dec 17, 2019·Breast Disease·Joško Bezić
Jun 26, 2021·Curēus·Mitsuhiro TachibanaYutaka Tsutsumi
Jun 19, 2021·International Medical Case Reports Journal·Mitsuhiro TachibanaYutaka Tsutsumi

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