Breast density across a regional screening population: effects of age, ethnicity and deprivation

The British Journal of Radiology
Samantha L HellerLouise S Wilkinson

Abstract

Breast density (BD) is a recognized risk factor for breast cancer. This study maps density variation across a screening population and identifies demographic distinctions, which may affect density and so impact on cancer development/detection. We focus on the relationship between age, ethnicity and socioeconomic status on density. This retrospective study on a screening population adheres to local patient confidentiality requirements. BD data from screening mammograms (March 2013 to September 2014) were measured using Volpara((®))Density(™) software (Volpara((®))Solutions(™), Wellington, New Zealand). Demographics, including patient age, ethnicity and deprivation index, were obtained from our breast screening database and analysed with respect to breast volume (BV), fibroglandular tissue volume (FGV), Volpara %BD and Volpara Grade (1-4 scale, lowest to highest). Study population demonstrates little difference for BV with respect to age, but a slight negative trend was noted when FGV was evaluated vs age. Density was linked to ethnicity: females of Chinese ethnicity had higher BD largely reflecting their lower BV. Females in the most deprived quintiles tended to have larger and therefore less dense breasts. Our mapping of BD in ...Continue Reading

References

May 1, 1994·The British Journal of Nutrition·A M Stephen, G M Sieber
Aug 23, 2005·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Martin Yaffe, Norman Boyd
Jan 19, 2007·The New England Journal of Medicine·Norman F BoydMartin J Yaffe
Jul 16, 2008·American Journal of Epidemiology·Valerie A McCormackIsabel dos Santos Silva
Feb 11, 2010·BMC Cancer·Zoe AitkenIsabel dos Santos Silva
Nov 26, 2011·Breast Cancer Research : BCR·Norman F BoydSalomon Minkin
Feb 18, 2012·Journal of Medical Screening·Jean-François Viel, Raouchan Rymzhanova
Feb 24, 2012·AJR. American Journal of Roentgenology·Cristina M CheckaHildegard Toth
Mar 1, 2012·Annals of Epidemiology·Amanda I PhippsChristopher I Li
Aug 13, 2013·Cancer Causes & Control : CCC·Joanne F DorganNola M Hylton
Apr 3, 2014·JAMA : the Journal of the American Medical Association·Lydia E Pace, Nancy L Keating

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Citations

Aug 2, 2017·Lymphatic Research and Biology·Elizabeth S DylkeSharon L Kilbreath
Jun 30, 2019·Breast Cancer Research and Treatment·Erni LiXiaohong R Yang
Nov 20, 2016·Breast Cancer Research and Treatment·Nadia RajaramSoo Hwang Teo
Sep 25, 2018·Acta Radiologica Open·Georg J WengertKatja Pinker
Aug 31, 2021·Journal of Psychosocial Oncology Research and Practice·Jami FukuiIan Pagano

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