Abstract
Breast density (BD) is a recognized risk factor for breast cancer. This study maps density variation across a screening population and identifies demographic distinctions, which may affect density and so impact on cancer development/detection. We focus on the relationship between age, ethnicity and socioeconomic status on density. This retrospective study on a screening population adheres to local patient confidentiality requirements. BD data from screening mammograms (March 2013 to September 2014) were measured using Volpara((®))Density(™) software (Volpara((®))Solutions(™), Wellington, New Zealand). Demographics, including patient age, ethnicity and deprivation index, were obtained from our breast screening database and analysed with respect to breast volume (BV), fibroglandular tissue volume (FGV), Volpara %BD and Volpara Grade (1-4 scale, lowest to highest). Study population demonstrates little difference for BV with respect to age, but a slight negative trend was noted when FGV was evaluated vs age. Density was linked to ethnicity: females of Chinese ethnicity had higher BD largely reflecting their lower BV. Females in the most deprived quintiles tended to have larger and therefore less dense breasts. Our mapping of BD in ...Continue Reading
References
May 1, 1994·The British Journal of Nutrition·A M Stephen, G M Sieber
Mar 13, 2002·Academic Radiology·John J Heine, Poonam Malhotra
Aug 23, 2005·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Martin Yaffe, Norman Boyd
Jan 19, 2007·The New England Journal of Medicine·Norman F BoydMartin J Yaffe
Jul 16, 2008·American Journal of Epidemiology·Valerie A McCormackIsabel dos Santos Silva
Feb 11, 2010·BMC Cancer·Zoe AitkenIsabel dos Santos Silva
Nov 26, 2011·Breast Cancer Research : BCR·Norman F BoydSalomon Minkin
Feb 18, 2012·Journal of Medical Screening·Jean-François Viel, Raouchan Rymzhanova
Feb 24, 2012·AJR. American Journal of Roentgenology·Cristina M CheckaHildegard Toth
Mar 1, 2012·Annals of Epidemiology·Amanda I PhippsChristopher I Li
Sep 21, 2012·The British Journal of Radiology·A RedondoX Castells
Apr 13, 2013·Radiology·Elena VenturiniAlessandro Del Maschio
Aug 13, 2013·Cancer Causes & Control : CCC·Joanne F DorganNola M Hylton
Aug 13, 2013·PloS One·Lis Ellison-LoschmannMona Jeffreys
Apr 3, 2014·JAMA : the Journal of the American Medical Association·Lydia E Pace, Nancy L Keating
May 17, 2014·Cancer·Tracy OnegaEmily F Conant
Sep 23, 2014·Breast Cancer Research : BCR·Amanda EngIsabel dos-Santos-Silva
Jul 3, 2015·The Breast Journal·Charlotte C GardCarolyn M Rutter
Citations
Aug 2, 2017·Lymphatic Research and Biology·Elizabeth S DylkeSharon L Kilbreath
Nov 6, 2018·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Mikinao OiwaShu Ichihara
Jun 30, 2019·Breast Cancer Research and Treatment·Erni LiXiaohong R Yang
Nov 20, 2016·Breast Cancer Research and Treatment·Nadia RajaramSoo Hwang Teo
Sep 25, 2018·Acta Radiologica Open·Georg J WengertKatja Pinker
May 29, 2018·European Radiology·Laura WardL Wilkinson
Feb 9, 2021·JNCI Cancer Spectrum·Ana S SalazarAdetunji T Toriola
Aug 31, 2021·Journal of Psychosocial Oncology Research and Practice·Jami FukuiIan Pagano