Breast health and associated premenstrual symptoms in women with severe cyclic mastopathy

American Journal of Obstetrics and Gynecology
P J GoodwinK Ritchie

Abstract

A case-control study was undertaken to examine the association of cyclic mastopathy with premenstrual syndrome and prior breast health. A total of 34 women with severe cyclic mastopathy (cases) and 29 women with no significant breast symptoms (controls) prospectively recorded breast pain and swelling and symptoms of premenstrual syndrome during one menstrual cycle. They also provided information on past breast health. The two study groups were compared by use of standard statistical methods. Women with cyclic mastopathy reported more frequent consultations with physicians for specific breast lumpiness (p = 0.02) or generalized lumpiness (p = 0.004) and for all breast problems (p = 0.0001) and more frequent mammograms (p = 0.04), surgical breast biopsies (p = 0.06), and breast needle aspirations (p = 0.05). Premenstrual symptoms were more severe in women with cyclic mastopathy; this was most pronounced for physical symptoms (water retention and breast symptoms, p < 0.001) but also present for negative affect, behavior change, and impaired concentration (p < 0.05). Women with cyclic mastopathy have a spectrum of breast concerns and they undergo more frequent breast investigations than do women without the disorder. Most symptoms ...Continue Reading

References

Nov 29, 1975·British Medical Journal·P E PreeceL E Hughes
Dec 1, 1992·Current Opinion in Obstetrics & Gynecology·J F Mortola
Sep 1, 1992·Clinical Obstetrics and Gynecology·J F Mortola
Jan 1, 1989·Journal of Clinical Epidemiology·P KerseyN F Boyd
Sep 1, 1988·The British Journal of Surgery·P J GoodwinN F Boyd
Jan 1, 1987·British Journal of Obstetrics and Gynaecology·J F WattsR Logan Edwards
Mar 15, 1984·The New England Journal of Medicine·G J Calton, J W Burnett
Nov 1, 1994·Drugs·P A Holland, C A Gateley
Aug 1, 1994·British Journal of Obstetrics and Gynaecology·D J BudeiriJ C Dornan
Feb 1, 1994·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·J F Mortola

❮ Previous
Next ❯

Citations

Jun 5, 2001·The British Journal of Radiology·K L CheungU S Khoo
Mar 14, 2007·Breast Cancer Research and Treatment·Robert ManselUNKNOWN Afimoxifene (4-OHT) Breast Pain Research Group
Jan 3, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·R EcochardJ F Guerin
Jul 22, 2005·The New England Journal of Medicine·Richard J Santen, Robert Mansel
May 20, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·S OksaJ Mäenpää
Feb 3, 2000·Journal of Psychosomatic Obstetrics and Gynaecology·D N AderM W Browne
Jul 12, 2001·Journal of Psychosomatic Obstetrics and Gynaecology·D N AderP A Deuster
Jun 16, 1999·Current Opinion in Obstetrics & Gynecology·U Halbreich
Aug 13, 2002·Obstetrical & Gynecological Survey·Antonio V Millet, Frederick M Dirbas
Aug 11, 2018·Advances in Therapy·Yasemin Altıntas, Mehmet Bayrak
Mar 11, 2004·Mayo Clinic Proceedings·Robin L SmithLorraine A Fitzpatrick
Feb 13, 2001·The Journal of Steroid Biochemistry and Molecular Biology·J A Gustafsson, M Warner
May 28, 2021·Journal of Family Medicine and Primary Care·Garima Jaiswal, Ghanshyam S Thakur
Jun 10, 2021·Journal of Complementary & Integrative Medicine·Shirin Osouli TabriziMojgan Mirghafourvand

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.