Breast implant-related silicone granulomas: the literature and the litigation

Plastic and Reconstructive Surgery
Eric David Austad

Abstract

Formation of a granuloma is a common tissue response to the presence of a variety of foreign materials. A silicone granuloma is, by definition, a type of tissue reaction elicited occasionally by silicone. Granulomas of this sort have not engendered a great deal of attention in the scientific literature since their first description in 1964, and they were considered by most surgeons through the 1980s to be an incidental finding of little or no consequence. Since it is tangible and readily visible to juries, the silicone granuloma became a frequent issue in breast implant litigation in the 1990s. Although most other complaints in this litigation have been subjective or causally unrelated to silicone, the presence of a granuloma has been used as a basis of local complication claims and, more creatively, as a mechanism for hypothetical systemic disease occurrence. This review examines the basic science and the clinical literature pertaining to breast implant-related silicone granulomas, viewing them in a context of current clinical thought and frequent issues of litigation. Clinically apparent silicone granulomas are a relatively rare complication of breast implant placement and surgical resection is indicated when they are symptom...Continue Reading

References

Sep 1, 1978·Plastic and Reconstructive Surgery·R J HausnerK K Pierson
Oct 1, 1978·British Journal of Plastic Surgery·W WintschL Clodius
Jun 1, 1977·Plastic and Reconstructive Surgery·H V Eisenberg, R J Bartels
Apr 1, 1992·Plastic and Reconstructive Surgery·D M Deapen, G S Brody
Jun 18, 1992·The New England Journal of Medicine·H BerkelH Jenkins
Jan 1, 1991·Aesthetic Plastic Surgery·C W Williams
Jan 1, 1988·Annals of Plastic Surgery·J W ThorntonM W Marks
Jan 1, 1985·Human Pathology·W D TravisJ L Abraham
Mar 1, 1986·Plastic and Reconstructive Surgery·D M DeapenG S Brody
May 1, 1985·Annals of Plastic Surgery·J Apesos, T L Pope
Sep 1, 1980·Plastic and Reconstructive Surgery·J A Edmond, A D Versaci
Jan 1, 1981·Aesthetic Plastic Surgery·H Jenny, J Smahel
Jul 1, 1980·Plastic and Reconstructive Surgery·G D Nelson
Dec 1, 1995·Plastic and Reconstructive Surgery·N HandelM J Silverstein
Oct 1, 1995·Plastic and Reconstructive Surgery·D T NetscherD Bowen
Oct 1, 1994·Plastic and Reconstructive Surgery·M CopelandI J Bleiweiss
Oct 1, 1993·Plastic and Reconstructive Surgery·D C BirdsellH Berkel
Apr 1, 1997·Plastic and Reconstructive Surgery·D M DeapenG S Brody
Jun 11, 1997·International Journal of Cancer. Journal International Du Cancer·S FriisJ H Olsen
Jul 1, 1997·Annals of Plastic Surgery·W PetersD Ibanez
Nov 30, 1999·Plastic and Reconstructive Surgery·R J Rohrich
Mar 4, 2000·Plastic and Reconstructive Surgery·D DeapenG S Brody
Mar 4, 2000·Journal of the Royal Society of Medicine·J M Price, E S Rosenberg
Mar 16, 2000·The New England Journal of Medicine·E C JanowskyB S Hulka
Dec 1, 1964·Archives of Dermatology·L H WINERF L ASHLEY

❮ Previous
Next ❯

Citations

Mar 11, 2005·Aesthetic Plastic Surgery·Lise ChristensenEstrid Hogdall
Jan 29, 2013·Aesthetic Plastic Surgery·George J ZambacosApostolos D Mandrekas
Feb 1, 2005·The Lancet Infectious Diseases·Brigitte PittetDidier Pittet
Feb 4, 2010·Plastic and Reconstructive Surgery·John FischerKenneth Shestak
Jan 1, 2011·Case Reports in Dermatological Medicine·Waseem Asim Ghulam El-CharnoubiJens Joergen Elberg
Feb 3, 2016·The British Journal of Oral & Maxillofacial Surgery·Latoni Kaysha Gilbert, Janavikulam Thiruchelvam
Dec 19, 2012·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·A Ozlem GundesliogluDilek Emlik
Nov 7, 2009·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Rony A Moscona, Lucian Fodor
Feb 9, 2011·ANZ Journal of Surgery·Lana P SturmGuy J Maddern
Aug 1, 2006·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Anindya Lahiri, Ruth Waters
Mar 4, 2009·The Journal of Bone and Joint Surgery. American Volume·Andrew W MackMichael R Lewin-Smith
Feb 3, 2004·The American Journal of Sports Medicine·Winston J WarmeTomas Ferguson
Apr 11, 2018·Plastic and Reconstructive Surgery. Global Open·Alice ThuerlimannDaniel F Kalbermatten
Aug 7, 2003·Expert Review of Vaccines·Frank DeStefanoRobert T Chen
Dec 20, 2007·Plastic and Reconstructive Surgery·Robert D BainsPaul Stanley
Nov 26, 2009·Aesthetic Plastic Surgery·Giovanni RapuzziVincenzo Jasonni
Nov 11, 2009·Aesthetic Plastic Surgery·Emmanuel DelayGilles Toussoun
Apr 27, 2010·Aesthetic Plastic Surgery·T P WolterC Neuhann-Lorenz
Dec 6, 2005·Annals of Plastic Surgery·Albert LoskenGrant W Carlson
Apr 18, 2020·Science Advances·Zhu ChengMatthew J Paszek
Aug 18, 2020·Plastic and Reconstructive Surgery. Global Open·Kishen Nara, Darryl Hodgkinson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Surgery
Lisbet R HölmichJørgen H Olsen
JAMA : the Journal of the American Medical Association
D H Gilden
Postgraduate Medical Journal
M Pirmohamed, P Winstanley
Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS
H Tehrani, B G H Lamberty
© 2022 Meta ULC. All rights reserved