Breast Milk and Breastfeeding of Infants Born to SARS-CoV-2 Positive Mothers: A Prospective Observational Cohort Study.

American Journal of Perinatology
Bgee KunjumonNazeeh Hanna

Abstract

There are limited published data on the transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus from mothers to newborns through breastfeeding or from breast milk. The World Health Organization released guidelines encouraging mothers with suspected or confirmed COVID-19 to breastfeed as the benefits of breastfeeding outweighs the possible risk of transmission. The objective of this study was to determine if SARS-CoV-2 was present in the breast milk of lactating mothers who had a positive SARS-CoV-2 nasopharyngeal swab test prior to delivery, and the clinical outcomes for their newborns. This was a single-center, observational, prospective cohort study. Maternal-newborn dyads that delivered at New York University Langone Hospital Brooklyn with confirmed maternal SARS-CoV-2 positive screen test at the time of admission were recruited for the study. Breast milk samples were collected during postpartum hospitalization and tested for the presence of SARS-CoV-2 genes N1 and N2 by two-step reverse transcription polymerase chain reaction. Additionally, the clinical characteristics of the maternal newborn dyad, results of nasopharyngeal SARS-CoV-2 testing, and neonatal follow-up data were collected. A tota...Continue Reading

References

Feb 23, 2020·JAMA : the Journal of the American Medical Association·Yan BaiMeiyun Wang
Apr 22, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Daihai HeLin Yang
May 25, 2020·Lancet·Rüdiger GroßJan Münch
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Jun 21, 2020·BMC Infectious Diseases·Wang DengDao-Xin Wang
Jul 3, 2020·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Aliye BastugHurrem Bodur
Jul 3, 2020·The Journal of Infection·Kieran A WalshPatricia Harrington
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Nov 17, 2020·Frontiers in Pediatrics·Enrico BertinoUNKNOWN Collaborative Research Group on SARS-CoV-2 in Human Milk

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