Breast MRI as an adjunct to mammography for breast cancer screening in high-risk patients: retrospective review

AJR. American Journal of Roentgenology
Antony RaikhlinRoberta A Jong

Abstract

In July 2011, the provincial government of Ontario, Canada, approved funding for the addition of annual breast MRI to mammography screening for all women 30-69 years old considered to be at high risk for breast cancer. The purpose of this study was to evaluate the diagnostic performance of screening breast MRI as compared with mammography in a population-based high-risk screening program. A retrospective review identified 650 eligible high-risk women who underwent screening breast MRI and mammography between July 2011 and January 2013 at one institution. Results of 806 screening rounds (comprising both MRI and mammography) were reviewed. Malignancy was diagnosed in 13 patients (invasive cancer in nine, ductal carcinoma in situ in three [one with microinvasion], and chest wall metastasis in one). Of the 13 cancers, 12 (92.3%) were detected by MRI and four (30.8%) by mammography. In nine of these patients, the cancer was diagnosed by MRI only, resulting in an incremental cancer detection rate of 10 cancers per 1000 women screened. MRI screening had significantly higher sensitivity than mammography (92.3% vs 30.8%) but lower specificity (85.9% vs 96.8%). MRI also resulted in a higher callback rate for a 6-month follow-up study (BI...Continue Reading

References

Jun 1, 1993·Cancer·P G PeerA L Verbeek
Jun 2, 1993·Journal of the National Cancer Institute·E J FeuerT Tong
Aug 10, 1996·Lancet·C C SunS A Narod
Jun 22, 1999·Lancet·J ChangH F Choo
Feb 22, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C T BrekelmansUNKNOWN Rotterdam Committee for Medical and Genetic Counseling
Aug 2, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·E WarnerS A Narod
Mar 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lauren ScheuerKenneth Offit
Jul 16, 2002·Radiologic Clinics of North America·Laura Liberman, Jennifer H Menell
Aug 23, 2002·Pathology·Jane E Armes, Deon J Venter
Sep 28, 2002·International Journal of Cancer. Journal International Du Cancer·Madeleine Tilanus-LinthorstCecile Brekelmans
Dec 4, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Smita BhatiaUNKNOWN Late Effects Study Group
Apr 2, 2004·Statistics in Medicine·Jonathan TyrerJack Cuzick
Jul 30, 2004·The New England Journal of Medicine·Mieke KriegeUNKNOWN Magnetic Resonance Imaging Screening Study Group
Jul 30, 2004·The New England Journal of Medicine·Laura Liberman
Sep 3, 2004·Nature Reviews. Cancer·Steven A Narod, William D Foulkes
Sep 16, 2004·JAMA : the Journal of the American Medical Association·Ellen WarnerSteven A Narod
Sep 24, 2004·British Journal of Cancer·A C AntoniouD F Easton
Mar 2, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·H F A VasenL Beex
Apr 1, 2005·Cancer·Constance D LehmanUNKNOWN International Breast MRI Consortium Working Group
Nov 19, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christiane K KuhlHans H Schild
Feb 24, 2007·The Breast : Official Journal of the European Society of Mastology·Anne I HagenPål Møller
Mar 30, 2007·CA: a Cancer Journal for Clinicians·Debbie SaslowUNKNOWN American Cancer Society Breast Cancer Advisory Group
Aug 8, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S J LordN Houssami
Dec 21, 2007·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Madeleine M A Tilanus-LinthorstFiona J Gilbert
May 3, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Roger L MilneJavier Benítez
May 7, 2008·Annals of Internal Medicine·Ellen WarnerDonald Plewes
Oct 23, 2008·Topics in Magnetic Resonance Imaging : TMRI·Ellen Warner
Mar 30, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ellen WarnerSteven A Narod

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Citations

Oct 23, 2015·AJR. American Journal of Roentgenology·Jay R Parikh, Wei T Yang
Oct 16, 2016·Clinical and Translational Imaging : Reviews in Nuclear Medicine and Molecular Imaging·A CollarinoL M Pereira Arias-Bouda
Jan 18, 2018·Journal of Women's Health·Christine M GunnTracy A Battaglia
May 13, 2018·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Bradley M WoodDominique G Homberger
Jun 25, 2020·Journal of Medical Radiation Sciences·Dana S Al-MousaPatrick C Brennan
Apr 26, 2017·Cancer Control : Journal of the Moffitt Cancer Center·Shannon FalconJennifer S Drukteinis
Apr 14, 2019·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Satoko ShimadaMasami Arai
Dec 18, 2020·Revista da Associação Médica Brasileira·Renato de Oliveira Pereira, Benedito Borges da Silva
Jan 15, 2021·Scientific Reports·Charoenchai PuttipanyalearsApiwat Mutirangura
Jan 30, 2016·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Rachel F BremJocelyn A Rapelyea
Jun 28, 2021·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·M KopecH Abramczyk
Jan 16, 2021·Archives of Pathology & Laboratory Medicine·Vanda F TorousGabrielle M Baker

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