Breast MRI, digital mammography and breast tomosynthesis: comparison of three methods for early detection of breast cancer

Bosnian Journal of Basic Medical Sciences
Dragana RoganovicDragan Stojanov


Breast cancer is the most common malignancy in women and early detection is important for its successful treatment. The aim of this study was to investigate the sensitivity and specificity of three methods for early detection of breast cancer: breast magnetic resonance imaging (MRI), digital mammography, and breast tomosynthesis in comparison to histopathology, as well as to investigate the intraindividual variability between these modalities. We included 57 breast lesions, each detected by three diagnostic modalities: digital mammography, breast MRI, and breast tomosynthesis, and subsequently confirmed by histopathology. Breast Imaging-Reporting and Data System (BI-RADS) was used for characterizing the lesions. One experienced radiologist interpreted all three diagnostic modalities. Twenty-nine of the breast lesions were malignant while 28 were benign. The sensitivity for digital mammography, breast MRI, and breast tomosynthesis, was 72.4%, 93.1%, and 100%, respectively; while the specificity was 46.4%, 60.7%, and 75%, respectively. Receiver operating characteristics (ROC) curve analysis showed an overall diagnostic advantage of breast tomosynthesis over both breast MRI and digital mammography. The difference in performance be...Continue Reading


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Apr 12, 2018·Diagnostics·Keun-Yeong JeongHwan Mook Kim
Jun 13, 2019·The Breast Journal·Akriti Gupta JainCheng Fang
Jun 4, 2019·The Journal of International Medical Research·Wei XiangFanrong Meng
Jun 30, 2018·Journal of Biomedical Optics·Eliana CorderoJürgen Popp
Dec 19, 2020·Open Medicine·Haotian LuYing Liu

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