Breast Prosthesis Syndrome: Pathophysiology and Management Algorithm

Aesthetic Plastic Surgery
Maria-Isabel Caravantes-CortesAdrian-Alejandro Carballo-Zarate

Abstract

The cosmetic use of devices like prostheses to increase breast volume is nothing new. It is calculated that millions of people have been exposed to silicone in several ways, including breast implants, and since 1964 there has been uncertainty regarding their safety. We did not find in the literature any studies that reported the appearance of a specific immunological disease in patients with silicone breast implants. Furthermore, there are also neither case-control studies nor reports of patients proving that symptoms of autoimmune/inflammatory syndrome induced by adjuvants (ASIA) occurred after the placement of silicone implants nor that the patients had pre-existing symptoms. Several studies link silicone to allergic reactions and the development of systemic autoimmune diseases; however, other studies deny this association. There are currently several theories about the effect of silicone on the body. One theory with greater acceptance proposes an adjuvant effect of silicone on the development of autoimmune diseases in genetically predisposed patients. However, the variety of symptoms occurring in patients who develop these pathologies leads to doubts about the relationship between the adjuvant effects of a silicone prosthesi...Continue Reading

References

Nov 1, 1979·Annals of Plastic Surgery·B F UretskyM D Becker
Jan 27, 1978·Science·M G WickhamJ L Abraham
Jun 1, 1993·Journal of Autoimmunity·S S TeuberM E Gershwin
Apr 1, 1996·Plastic and Reconstructive Surgery·L T YuN S Hardt
May 1, 1997·Annals of Plastic Surgery·W H BeekmanJ J Hage
Aug 1, 1997·Plastic and Reconstructive Surgery·J A Keech, B J Creech
Nov 5, 1997·Plastic and Reconstructive Surgery·G S Brody
Dec 19, 1998·Plastic and Reconstructive Surgery·R J RohrichJ M Kenkel
Jul 27, 1999·Annals of the Rheumatic Diseases·C J SchaeferP H Wooley
Mar 16, 2000·The New England Journal of Medicine·E C JanowskyB S Hulka
Jul 12, 2002·Clinical Rheumatology·C M E ContantA M M Eggermont
Nov 26, 2002·Endocrine Pathology·Ally P H PrebtaniShereen Ezzat
Nov 6, 2004·Arthritis and Rheumatism·Terrance O'HanlonUNKNOWN Environmental Myositis Study Group
Jul 5, 2007·Clinical Rheumatology·Mehmet BekereciogluOmer Bulut
Jul 17, 2007·Cell·Christopher C Goodnow
Mar 26, 2008·The Journal of Experimental Medicine·Mirjam KoolBart N Lambrecht
Nov 6, 2008·JAMA : the Journal of the American Medical Association·Daphne de JongFlora E van Leeuwen
Nov 7, 2008·Journal of Biomedical Materials Research. Part a·Kristy M AinslieTejal A Desai
May 14, 2009·Aesthetic Plastic Surgery·Per HedénLeo Peter van der Weij
Jul 23, 2009·BMJ : British Medical Journal·David MoherUNKNOWN PRISMA Group
Aug 17, 2010·Journal of Autoimmunity·Yehuda Shoenfeld, Nancy Agmon-Levin
Oct 1, 2010·European Journal of Clinical Investigation·Steven D HajduYehuda Shoenfeld
Oct 15, 2010·International Journal of Epidemiology·I-Min LeeJulie E Buring
Mar 2, 2011·Plastic and Reconstructive Surgery·Benjamin KimSoeren Mattke
Apr 20, 2011·Plastic and Reconstructive Surgery·Benjamin KimSoeren Mattke
Dec 14, 2011·International Journal of Hygiene and Environmental Health·Michelle C RochaMary L S Queiroz
Jan 31, 2012·Plastic and Reconstructive Surgery·Dolores WolframGeorg Wick
Jan 29, 2013·Aesthetic Plastic Surgery·George J ZambacosApostolos D Mandrekas
Apr 6, 2013·Expert Review of Clinical Immunology·Olga Vera-LastraYehuda Shoenfeld
Apr 12, 2013·Immunologic Research·J W Cohen Tervaert, R M Kappel
Sep 4, 2015·Journal of Autoimmunity·Mojca BizjakYehuda Shoenfeld
Sep 27, 2015·Clinics in Plastic Surgery·Mark W Clemens, Roberto N Miranda
Nov 10, 2015·Annals of Internal Medicine·Ethan M BalkGowri Raman
Nov 26, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C LaurentL Lamant
Dec 3, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mark W ClemensRoberto N Miranda

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Citations

Apr 29, 2020·Aesthetic Plastic Surgery·Maria-Isabel Caravantes-CortesShirley-Yoselin Salazar-Ruiz
Apr 29, 2020·Aesthetic Plastic Surgery·Nevio Cimolai
Oct 16, 2020·Biomolecules·Vânia BorbaYehuda Shoenfeld
Apr 3, 2021·Journal of Autoimmunity·Gilad HalpertYehuda Shoenfeld

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