Breast Reconstruction Following Breast Implant-Associated Anaplastic Large Cell Lymphoma

Plastic and Reconstructive Surgery
Gregory A LamarisMark W Clemens

Abstract

Standard of care treatment of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) involves surgical resection with implant removal and complete capsulectomy. We report a case series of BIA-ALCL reconstruction with proposals for timing and technique selection. We retrospectively reviewed and prospectively enrolled all BIA-ALCL patients at 2 tertiary care centers and 1 private plastic surgery practice from 1998 to 2017. Demographics, treatment, reconstruction, pathology staging, patient satisfaction, and oncologic outcomes were reviewed. We treated 66 consecutive BIA-ALCL patients and 18 (27%) received reconstruction. Seven patients (39%) received immediate reconstruction, and 11 (61%) received delayed reconstruction. Disease stage at presentation was IA (T1N0M0 disease confined to effusion or a layer on luminal side of capsule with no lymph node involvement and no distant spread) in 56%, IB in 17%, IC (T3N0M0 cell aggregates or sheets infiltrating the capsule, no lymph node involvement and no distant spread) in 6%, IIA (T4N0M0 lymphoma infiltrating beyond the capsule, no lymph node involvement and no distant spread) in 11%, and III in 11%. Types of reconstruction included smooth implants (72%), immediate mastopex...Continue Reading

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Citations

Dec 18, 2019·Aesthetic Plastic Surgery·Guillermo Ramos-GallardoEnrique Javier Cedillo-Alemán
Jun 27, 2020·Plastic and Reconstructive Surgery·Erica LeeJustin M Sacks
Dec 29, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Philip TurtonNigel Mercer
Aug 1, 2020·Clinical Oncology : a Journal of the Royal College of Radiologists·M CoA Kwong
Mar 26, 2021·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Antonella CampanaleLucia Lispi
Apr 24, 2021·Plastic and Reconstructive Surgery·Malke AsaadMark W Clemens

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