PMID: 9423209Jan 10, 1998Paper

Breast tumour imaging using incomplete circular orbit pinhole SPET: a phantom study

Nuclear Medicine Communications
C ScarfoneR E Coleman

Abstract

Improvements in 99Tcm-sestamibi breast lesion visualization using single photon emission tomography (SPET) may help define the clinical role of this technique alongside X-ray mammography in the diagnosis and management of breast cancer. Pinhole SPET offers the advantages of high resolution and sensitivity when compared to conventional parallel-beam collimation for sources located near the pinhole aperture. In this work, the potential of incomplete (180 degrees) circular orbit (ICO) SPET with pinhole collimation is investigated as a means to visualize small (6.4 and 9.6 mm diameter) spherical simulated tumours, at clinical count densities and tumour-to-background ratios, in a breast phantom. ICO pinhole SPET is compared to complete circular orbit (CCO) pinhole SPET for reference, and planar breast imaging (scintimammography) using parallel-beam and pinhole collimators. A prototype box-shaped pinhole collimator with a 4 mm diameter circular aperture was used to acquire projections of an 890 ml breast phantom both in isolation and mounted on a cylinder filled with a mixture of 99Tcm-pertechnetate and water. A heart phantom containing 99Tcm activity in the myocardium was placed in the cylinder. Simulated tumours containing 99Tcm we...Continue Reading

Citations

Jun 12, 2004·IEEE Transactions on Medical Imaging·Roberto Accorsi, Scott D Metzler
Aug 22, 2001·IEEE Transactions on Medical Imaging·S D MetzlerR J Jaszczak
Jul 14, 2005·IEEE Transactions on Medical Imaging·S D MetzlerB B Chin
Jul 14, 2005·IEEE Transactions on Medical Imaging·Caryl N BrzymialkiewiczJames E Bowsher
Feb 25, 2015·World Journal of Nuclear Medicine·Jalil Pirayesh IslamianEsmail Gharapapagh

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