Breastfeeding and vitamin D supplementation reduce the risk of Kawasaki disease in a German population-based case-control study

BMC Pediatrics
K MeyerA Jakob

Abstract

In Kawasaki disease (KD), a vasculitis of unknown etiology, the most serious complication is the development of coronary artery aneurysm (CAA). To date, the exact pathomechanism of KD is unknown. Both environmental and genetic factors seem to be associated with the development of the disease. Data on KD patients recruited from the population-based German Pediatric Surveillance Study during 2012-2014 were used to evaluate the impact of various factors from the perinatal and infancy period on the development of KD. The study design was a matched case-control study with respect to age, sex and place of residence (n = 308 KD cases, n = 326 controls). All KD patients were individually re-evaluated; all fulfilled the international diagnostic KD criteria. A standardized questionnaire was used to review breastfeeding practices, vitamin D supplementation and birth characteristics. Logistic regression analyses were performed to obtain odds ratios (OR) for various risk factors among the case-control pairs. Simple measures of association were used to assess the impact of these factors on the clinical course. There was no difference in lengths of gestation, birth weight or parturition between KD patients and controls, but independently from...Continue Reading

References

Nov 1, 1979·Digestive Diseases and Sciences·R E Kleinman, W A Walker
Apr 30, 1992·The New England Journal of Medicine·J G Haddad
Apr 22, 1999·The New England Journal of Medicine·D D McIntireK J Leveno
Aug 11, 2004·Lancet·Jane C Burns, Mary P Glodé
May 8, 2009·Pediatrics International : Official Journal of the Japan Pediatric Society·Tatsuo NishimuraHarumi Kaji
Dec 2, 2010·The Journal of Clinical Endocrinology and Metabolism·A Catharine RossSue A Shapses
Jul 2, 2011·Journal of the American College of Cardiology·Ibhar Al MheidArshed A Quyyumi
Aug 17, 2012·The Cochrane Database of Systematic Reviews·Michael S Kramer, Ritsuko Kakuma
Dec 3, 2014·Pediatrics·Astrid SevelstedHans Bisgaard
Feb 11, 2015·The Journal of Clinical Endocrinology and Metabolism·Markus JuonalaOlli T Raitakari
Oct 16, 2015·The Pediatric Infectious Disease Journal·André JakobMarkus Hufnagel
Dec 15, 2015·Journal of Clinical Laboratory Analysis·Fatma Alibaz-OnerHaner Direskeneli
Feb 27, 2016·BMJ : British Medical Journal·Neil Pearce
May 29, 2016·The Journal of Pediatrics·Paolo Manzoni
Jul 25, 2017·Journal of Autoimmunity·Francesco ColottaFabrizio Bonelli
Sep 2, 2017·Korean journal of pediatrics·Jae Sung JunDong Won Lee
Feb 14, 2018·Pediatrics in Review·Mary Beth F Son, Jane W Newburger
Nov 24, 2018·The Science of the Total Environment·Takashi YorifujiHiroyuki Doi

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Citations

Dec 5, 2019·European Journal of Pediatrics·Shun WangBaozhen Yao
Jul 22, 2019·Pediatric Rheumatology Online Journal·Wei-Dong HuangHo-Chang Kuo
Jun 27, 2021·Scientific Reports·Sayaka FukudaUNKNOWN Japan Environment and Children’s Study (JECS) Group
Oct 31, 2021·Nature Reviews. Rheumatology·Chetan SharmaJagadeesh Bayry

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