Breath analysis: technical developments and challenges in the monitoring of human exposure to volatile organic compounds

Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Zhentao TangYixiang Duan

Abstract

At present, there is a growing concern about human quality of life. In particular, there is an awareness of the impact of volatile organic compounds (VOCs) on the environment and human health, so the monitoring of human exposure to VOCs is an increasingly urgent need. Biomonitoring is theoretically more accurate compared with traditional ambient air monitoring, and it plays an essential role in human environmental exposure assessment. Breath analysis is a biomonitoring method with many advantages, which is applicable to assessments of human exposure to a large number of VOCs. Techniques are being developed to improve the sensitivity and precision of breath analysis based on in-direct and direct measurements which will be reviewed in this paper. This paper briefly reviews the frequently used methods in both of these categories, specifically highlighting some promising new techniques. Furthermore, this review also provides theoretical background knowledge about the use of breath analysis as a biomonitoring tool for human exposure assessment. A review of the application of breath analysis to human exposure monitoring during last two decades is also provided according to occupational/non-occupational exposure. Obstacles and potenti...Continue Reading

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Citations

Apr 21, 2016·Environmental Science & Technology·Alexander York BigazziJames F Pankow
Jul 17, 2018·Journal of Breath Research·Thomas Hector ChappuisBertrand Bourlon
Nov 18, 2016·Journal of medical and biological engineering·Souvik DasMadhuchhanda Mitra
Dec 17, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alessia Di GilioGianluigi de Gennaro
Jun 10, 2021·Gut·Alex J ThompsonUNKNOWN HUNGer Consortium

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