Breathing pattern and cost of ventilation in the American alligator

Respiration Physiology
T Wang, S J Warburton

Abstract

The energetic cost of pulmonary ventilation is termed the "cost of breathing" and is commonly determined from the change in oxygen uptake with altered ventilation. Previous analyses of lung mechanics predicts increased tidal volume would be more expensive than increased breathing frequency. Existing studies on the oxidative cost of breathing have, however, not addressed breathing pattern. We stimulated ventilation in juvenile alligators by either hypoxia or hypercapnia. Both hypoxia and hypercapnia increased ventilation (ten- and six-fold, respectively), but through entirely different changes in frequency and tidal volume combination. Hypoxia increased frequency from 1.4 to 6.0 breaths min -1 and tidal volume from 11.3 to 25.9 ml kg -1. During hypercapnia frequency remained constant, while tidal volume increased from 8.7 to 63.2 ml kg -1. Oxygen uptake remained constant at approximately 0.65 ml O2 kg -1 min -1 during all hypercapnic exposures, whereas oxygen uptake doubled during severe hypoxia. Extrapolating oxygen uptake to zero ventilation provides an estimate of non-ventilatory metabolic rate. Thus, ventilatory contributions to overall metabolic rate can be calculated. The cost of breathing estimated by hypoxic exposures (1...Continue Reading

References

Dec 1, 1977·Respiration Physiology·J L Kinney, F N White
Jul 1, 1978·Respiration Physiology·S F Perry, H R Duncker
May 1, 1976·Respiration Physiology·C Gans, B Clark
Apr 1, 1992·Respiration Physiology·J W Hicks, F N White
Jan 1, 1956·Journal of Applied Physiology·A B OTISE P RADFORD

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Citations

Mar 31, 2010·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·I H TomascoF Bozinovic
Mar 4, 2000·Respiration Physiology·L H Gargaglioni, L G Branco
Jul 4, 2002·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Wilfried KleinE W Taylor
Aug 13, 2004·Proceedings. Biological Sciences·Leon P A M Claessens
Sep 26, 2013·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Todd L SchmittJames Hicks
Nov 12, 2005·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Glenn J TattersallWilliam K Milsom
Oct 28, 2009·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Jessamyn S Markley, David R Carrier
Jun 15, 2007·Respiratory Physiology & Neurobiology·Nini Skovgaard, Tobias Wang
Jun 29, 2007·Respiratory Physiology & Neurobiology·Carlos A Navas, José Guilherme Chauí-Berlinck
Nov 3, 2015·Respiratory Physiology & Neurobiology·Stella Y Lee, William K Milsom
Aug 20, 2015·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Joanna PiercyWilliam K Milsom
Nov 24, 2004·Respiratory Physiology & Neurobiology·Tobias Wang, James W Hicks
Jul 6, 2004·Respiratory Physiology & Neurobiology·Nini Skovgaard, Tobias Wang
Jan 31, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·L K HartzlerJ W Hicks
Sep 22, 2009·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Leon P A M Claessens
Dec 24, 2014·Respiratory Physiology & Neurobiology·Tábata E F CordeiroWilfried Klein
May 28, 2008·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Tomasz Owerkowicz, Russell V Baudinette
Feb 21, 2016·The Journal of Experimental Biology·Nini SkovgaardTobias Wang
Sep 14, 2012·The Journal of Experimental Biology·Suzanne L Munns
Oct 6, 2009·The Journal of Experimental Biology·Catalina Reyes, William K Milsom
May 29, 2003·The Journal of Experimental Biology·Wilfried KleinSteven F Perry

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