BRI1-EMS-suppressor 1 gain-of-function mutant shows higher susceptibility to necrotrophic fungal infection

Biochemical and Biophysical Research Communications
Seo Youn ShinKyoung Hee Nam

Abstract

Brassinosteroids (BRs) are plant-specific steroids that are involved in plant growth and defense responses. However, the exact roles of BR in plant defense are unclear. We used the bes1-D gain-of-function mutant to define the underlying relationship between plant growth and defense through BR signaling and innate immunity. In bes1-D, further downstream component BES1 transcription factor is stabilized, leading to the activation of BR signaling. Previous reports on BES1 target genes showed that approximately 10% are related to biotic stress responses. Therefore, the bes1-D PTI responses were examined. The bes1-D mutant was specifically susceptible to Alternaria brassicicola, a necrotrophic fungus, which successfully produced spore, resulting in considerable cell death. However, it was not affected by a biotrophic pathogen, Pseudomonas syringae pv. tomato (Pst) DC3000. Instead of a ROS burst, a representative initial PTI responses, higher ROS accumulation was sustained in bes1-D than in the wild type plant. PDF1.2 expression was not induced in response to fungal pathogen infection in bes1-D. These results suggest that BES1 is also involved in JA-related defense responses, especially in response to necrotrophic pathogens.

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Citations

Dec 8, 2016·Molecular Plant Pathology·Bangjun Zhou, Lirong Zeng
Aug 8, 2018·Journal of Experimental Botany·Mari-Cruz CastilloJosé León
Jul 29, 2017·The Biochemical Journal·Trevor NolanYanhai Yin
Dec 20, 2018·International Journal of Molecular Sciences·Mei-Hui YuJun-Xian He
Nov 27, 2020·Journal of Cell Science·Fausto Andres Ortiz-MoreaEugenia Russinova

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