Bridge to transplantation with the MicroMed DeBakey ventricular assist device axial pump: a single centre report

Journal of Cardiovascular Medicine
Giuseppe BruschiEttore Vitali

Abstract

Left ventricular assist devices (VADs) are an accepted therapy to bridge patients with end-stage heart failure to heart transplantation. The DeBakey VAD, a continuous axial flow pump weighing 93 g, has been introduced into clinical practice as a bridge to transplant. Starting from April 2000,17 patients (12 males, five females, mean age 44.3 +/- 12.8 years; 11 dilated idiopathic cardiomyopathy, five ischaemic cardiomyopathy, one pulsatile device failure) with end-stage heart failure were implanted with a DeBakey VAD as a bridge to transplantation at our institution. Before implant, all patients suffered from severe heart failure (New York Heart Association functional class IV) despite optimal medical therapy and were put on the waiting list for heart transplantation. Mean cardiac index was 1.59 +/- 0.51 l/min/m2. Fourteen patients were successfully transplanted after 99 +/- 117 days of assistance (range 11-443 days). Two patients died during assistance of multiorgan failure, one patient is still on VAD. No patient needed additional right ventricular mechanical support. Left ventricular/left VAD thrombosis occurred in one patient who was successfully treated conservatively. No clinical elevation of plasma free haemoglobin was de...Continue Reading

References

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Citations

Feb 19, 2010·Journal of Cardiothoracic and Vascular Anesthesia·Christopher A ThunbergAlina M Grigore
Apr 30, 2008·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Donald S EsmoreFranklin L Rosenfeldt
May 28, 2008·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Donald EsmoreJohn Woodard
Aug 29, 2007·Heart Failure Clinics·Manuel Prinz von BayernMario C Deng
Jun 5, 2007·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Elzbieta PolskaLeopold Schmetterer
May 23, 2007·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Guo Rong Li, Xiao Dong Zhu
Nov 13, 2009·Current Opinion in Anaesthesiology·Nanhi Mitter, Rosanne Sheinberg

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