Bridging larger gaps in peripheral nerves using neural prosthetics and physical therapeutic agents

Neural Regeneration Research
Muhammad Sana Ullah SaharGeoffrey Douglas Tansley

Abstract

Peripheral nerve injuries are relatively common and can be caused by a variety of traumatic events such as motor vehicle accidents. They can lead to long-term disability, pain, and financial burden, and contribute to poor quality of life. In this review, we systematically analyze the contemporary literature on peripheral nerve gap management using nerve prostheses in conjunction with physical therapeutic agents. The use of nerve prostheses to assist nerve regeneration across large gaps (> 30 mm) has revolutionized neural surgery. The materials used for nerve prostheses have been greatly refined, making them suitable for repairing large nerve gaps. However, research on peripheral nerve gap management using nerve prostheses reports inconsistent functional outcomes, especially when prostheses are integrated with physical therapeutic agents, and thus warrants careful investigation. This review explores the effectiveness of nerve prostheses for bridging large nerve gaps and then addresses their use in combination with physical therapeutic agents.

References

Jan 1, 1989·Microsurgery·M MerleP S Chang
Nov 1, 1988·Plastic and Reconstructive Surgery·A L Dellon, S E Mackinnon
Jan 1, 1988·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·B L Eppley, J J Delfino
May 1, 1987·Experimental Neurology·S YoshiiM Hayashi
Apr 7, 1987·Brain Research·C B Jenq, R E Coggeshall
Apr 1, 1986·Experimental Neurology·R D Fields, M H Ellisman
Jun 1, 1984·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·A M Raji
May 1, 1996·Biomaterials·N Nicoli AldiniR Giardino
Apr 21, 1999·British Journal of Plastic Surgery·S Stanec, Z Stanec
Feb 15, 2001·The Journal of Hand Surgery·S YoshiiT Nakamura
Jun 4, 2002·British Journal of Plastic Surgery·R C YoungG Terenghi
Sep 6, 2002·Brain Research·Satoru YoshiiMasao Akagi
Dec 7, 2002·Ultrasound in Medicine & Biology·Ana Rosa Crisci, Affonso Luiz Ferreira
May 14, 2005·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·James W Strickland
May 14, 2005·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Susan L Michlovitz
Jun 1, 2005·The Journal of Hand Surgery·Mariëtta J O E BertleffJean-Phillipe A Nicolai
Oct 19, 2006·Journal of Neurosurgery·Michael O KelleherMichael A Glasby
Dec 13, 2006·The International Journal of Artificial Organs·K D NewmanM Griffith
Feb 27, 2007·The Journal of Thoracic and Cardiovascular Surgery·Makoto YoshitaniTatsuo Nakamura
Oct 9, 2007·Experimental Neurology·Peter AhlbornAndrey Irintchev
Jun 24, 2008·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Kenji SeoGenji Someya
Jul 30, 2008·Neurorehabilitation and Neural Repair·Ming-Chin LuYueh-Sheng Chen
May 30, 2009·Biomedical Microdevices·Valeria ChionoGianluca Ciardelli
Aug 18, 2009·International Review of Neurobiology·Shimon RochkindAsher Shainberg
Jan 27, 2010·Journal of Materials Science. Materials in Medicine·Lei Zheng, Hui-Fei Cui
Jun 17, 2010·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Sang Chul ParkJin Ho Lee
Feb 25, 2011·Annals of Biomedical Engineering·K E TanseyM I Romero
Aug 14, 2012·Journal of Biomedical Materials Research. Part a·Chiung-Chyi ShenBai-Shuan Liu
Dec 5, 2012·Acta Cirúrgica Brasileira·Marcos Vinícius Muniz GangaLuiza da Silva Lopes
Feb 22, 2013·Journal of Biomedical Materials Research. Part a·Chiung-Chyi ShenBai-Shuan Liu
Apr 5, 2013·Journal of Biomedical Materials Research. Part a·D ArslantunaliV Hasirci
Jul 31, 2013·Hand Clinics·Ron M G MenorcaJohn C Elfar
Aug 22, 2013·Journal of Biomedical Materials Research. Part a·Hieu T NguyenChristine E Schmidt
Aug 31, 2013·Carbohydrate Polymers·Alberto BusilacchiRiccardo A A Muzzarelli

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Citations

Jan 22, 2020·Neural Regeneration Research·Jian WengXiao-Feng Yin

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