Bridging the gap between neuroimaging and neuropsychology: using working memory as a case-study

Journal of Clinical and Experimental Neuropsychology
Julie A Fiez

Abstract

Neuropsychology and neuroimaging both provide information about the relationship between brain structure and function, and thus attempt to understand if the neural basis of cognition should benefit from converging results obtained across the two methods. However, serious attempts to integrate the two methodologies face several challenges, such as differences in basic paradigm designs. To illustrate these points, this article will review neuropsychological and neuroimaging research in the area of working memory. Points of discussion will include discrepancies between neuropsychological and neuroimaging evidence for domain-specific rehearsal systems, the role of left inferior parietal cortex in phonological storage, and the contributions of Brocas area and the cerebellum to articulatory rehearsal. Methodological factors and assumptions that may account for these discrepancies, and the steps that could be taken to overcome them, will be evaluated. The overall objective of this "case study" is to encourage neuroimagers and neuropsychologists to evaluate seriously the results obtained in both methodologies when formulating interpretations of their data and when designing new studies.

Citations

Mar 10, 2004·NeuroImage·Daniel V MeeganMichael Topan
Jun 18, 2004·Journal of Cognitive Neuroscience·Robert L HesterHugh Garavan
Apr 22, 2005·Developmental Neuropsychology·Robert M JosephHelen Tager-Flusberg
Oct 18, 2013·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Stephen J WilsonRobert R MacLean
Dec 3, 2003·Trends in Cognitive Sciences·Andrew R A ConwayRandall W Engle
Apr 25, 2007·International Journal of Audiology·Doris-Eva BamiouLinda M Luxon
Nov 30, 2006·Brain Injury : [BI]·Emmaline Kate FalconerKen McFarland
Apr 5, 2005·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·A FinkA C Neubauer
May 24, 2016·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Corrine DuriskoJulie A Fiez
Nov 11, 2005·Human Brain Mapping·Fatima T HusainBarry Horwitz
Apr 11, 2006·Neuroreport·Fatima T HusainBarry Horwitz

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