Brief Behavioral Therapy for Insomnia in Patients with Irritable Bowel Syndrome: A Pilot Study.

Digestive Diseases and Sciences
Sarah BallouAnthony Lembo

Abstract

Up to 60% of patients with irritable bowel syndrome (IBS) report fatigue and 50% meet criteria for clinical insomnia. Recent studies have demonstrated a relationship between poor sleep and next-day IBS symptoms. However, no study to-date has evaluated behavioral therapy to treat poor sleep in IBS. The aim of the current pilot study is to test feasibility of behavioral therapy for insomnia among patients with IBS and poor sleep. This randomized controlled pilot study tested the feasibility of administering brief behavioral therapy for insomnia (BBT-I) to patients with IBS who report poor sleep. Participants were randomized to BBT-I or self-monitoring control. Exploratory analyses evaluated group differences after 4 weeks of treatment. A total of 25 participants were randomized to the study, 13 to BBT-I and 12 to the control group. Three participants dropped out of the treatment group. Satisfaction with treatment was high. At follow-up, there were significant differences between groups in measures of sleep quality and insomnia severity. There were trends toward significance in IBS severity score, with 40% of the BBT-I sample reporting clinically meaningful drop in symptoms compared to 17% of the control group. Similar trends were...Continue Reading

References

May 16, 2000·The American Journal of Gastroenterology·R FassE A Mayer
May 29, 2002·Alimentary Pharmacology & Therapeutics·H B El-SeragD Bjorkman
Dec 21, 2002·The American Journal of Gastroenterology·Jennifer J ThompsonWilliam C Orr
Jun 30, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Yuri A SaitoG Richard Locke
Jul 1, 2004·Alimentary Pharmacology & Therapeutics·J S LabusB D Naliboff
Apr 24, 2008·Anesthesiology·Frances ChungColin M Shapiro
Feb 11, 2009·The Journal of Clinical Psychiatry·Lesley M ArnoldDon L Goldenberg
Feb 6, 2010·Sleep Medicine·Carla R JungquistMichael L Perlis
Jan 26, 2011·Archives of Internal Medicine·Daniel J BuysseTimothy H Monk
May 24, 2011·Journal of Neurogastroenterology and Motility·Yukari TanakaDouglas A Drossman
Dec 16, 2011·World Journal of Gastroenterology : WJG·Massimo BelliniSantino Marchi
Mar 8, 2012·European Journal of Pain : EJP·M HaackJ M Mullington
Sep 6, 2012·Behavioral Sleep Medicine·Wendy M TroxelDaniel J Buysse
Apr 13, 2013·Behaviour Research and Therapy·Jeffrey M LacknerDarren M Brenner
Jul 30, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·J VuG S Sayuk
Aug 22, 2014·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Diana Taibi BuchananMonica Jarrett
Sep 10, 2014·The American Journal of Gastroenterology·Brennan M R SpiegelDinesh Khanna
Dec 6, 2014·Sleep Medicine Clinics·Patrick H FinanMichael T Smith
Jun 9, 2015·Annals of Internal Medicine·James M TrauerDavid Cunnington
May 5, 2016·Gastroenterology·Olafur S PalssonYunsheng Yang
Jun 1, 2016·Alimentary Pharmacology & Therapeutics·A PatelG S Sayuk
Jul 13, 2016·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Å FrändemarkS Jakobsson
Apr 15, 2017·Disability and Rehabilitation·Sigrún Vala BjörnsdóttirUnnur Anna Valdimarsdóttir
Aug 11, 2018·Digestive Diseases and Sciences·Sarah BallouAnthony Lembo
Aug 17, 2019·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Sarah BallouJohanna Iturrino

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Citations

Jul 6, 2020·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Pei-Lin YangMargaret M Heitkemper
Dec 2, 2020·International Journal of Environmental Research and Public Health·Eun Hee JangSooyeon Suh
Feb 25, 2021·Nature and Science of Sleep·Michelle DrerupAmy B Sullivan
Jul 3, 2021·Sleep Medicine Reviews·Andrea BallesioCaterina Lombardo
Sep 15, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Vikram RanganAnthony Lembo

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