Brief report: a case study of an adolescent male with XXXXY Klinefelter's syndrome

Journal of Autism and Developmental Disorders
M K Sheridan, S S Radlinski

Abstract

The developmental history of a 14-year-old male with Klinefelter's syndrome (XXXXY) is described. A review of the XXXXY literature focuses on the physical complications and the mental deficiency associated with this syndrome. This case study describes an individual whose physical development is consistent with many patterns described in the XXXXY literature, although his retardation is not as severe as generally described. His personality and learning style are more similar to descriptions of XXY Klinefelter individuals. A detailed analysis of more XXXXY cases is essential to clarify developmental patterns and learning capacity in individuals with XXXXY syndrome. Severe retardation may no longer need to be the anticipated developmental outcome.

References

Jan 1, 1977·The Journal of Surgical Research·W J TempleA R Downs
Apr 16, 1973·Humangenetik·R ChrzJ Málková
Dec 1, 1973·Archives of Disease in Childhood·M Garvey, D E Mutton
Feb 1, 1970·The Journal of Pediatrics·S A MyhreV C Kelley
Jan 1, 1970·Major Problems in Clinical Pediatrics·D W Smith
Aug 1, 1971·American Journal of Diseases of Children·L R ShapiroK Hirschhorn
Jul 1, 1983·Behavior Genetics·A RobinsonJ Salbenblatt
Feb 1, 1982·Developmental Medicine and Child Neurology·S G Ratcliffe
Nov 1, 1982·American Journal of Medical Genetics·F Hecht
Nov 1, 1982·American Journal of Medical Genetics·P D Pallister
Jan 1, 1980·Human Genetics·E ThermanM Ulber
Jul 1, 1980·Clinical Genetics·H Autio-HarmainenP Aula
Oct 22, 1960·Lancet·M FRACCAROJ LINDSTEN
Jul 1, 1960·Annals of Human Genetics·M FRACCAROJ LINDSTEN

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Citations

Dec 1, 1990·Journal of Autism and Developmental Disorders·R A CollacottD Duckett
Dec 17, 2005·Hormone Research·Hee Jin KimGilho Lee
Jul 15, 2020·American Journal of Medical Genetics. Part a·Andrea L GropmanCarole A Samango-Sprouse
Jun 1, 1990·Journal of Mental Deficiency Research·L M CurfsJ P Fryns
Jun 1, 1990·Developmental Medicine and Child Neurology·M K SheridanM D Kennedy
Apr 20, 2001·International Journal of Paediatric Dentistry·S HataH Mayanagi

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