Brief report: assessing adherence to pediatric antiretroviral regimens using the 24-hour recall interview

Journal of Pediatric Psychology
Stephanie L MarhefkaClaude Ann Mellins

Abstract

Examine the 24-hr Recall Interview (24RI) for assessing children's antiretroviral medication adherence. Caregivers of 54 children with HIV (aged 2-12 years) completed a clinical adherence interview and the 24RI by telephone. Children's viral load and 3-month pharmacy records were obtained. Thirty-seven percent of children missed > or = 1 dose of medicine over 3 days. In 22% of the samples, adherence varied across medications. The 24RI adherence scores (Frequency, Interval, and Dietary Adherence) were moderately reliable across the three interviews. Pharmacy refill rates were significantly related to viral load, and 24RI barriers were marginally significantly related to viral load. The 24RI, with its systematic, cued recall, and decreased focus on adherence, may reduce socially desirable responding compared to other self-report methods, and reporting adherence barriers may indicate adherence difficulty. However, the validity of the 24RI must be improved to make it a useful measure to include in an adherence assessment battery.

References

Oct 1, 1992·Journal of Pediatric Psychology·S B JohnsonJ H Silverstein
Apr 3, 2002·Pediatrics·Russell B Van DykeUNKNOWN Pediatric AIDS Clinical Trials Group Adherence Subcommittee Pediatric AIDS Clinical Trials Group 377 Study Team
Sep 13, 2002·Journal of Medical Virology·Jane MullenPhilippa Easterbrook
Apr 26, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Francisco-Javier San-AndrésAngel del Palacio
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Apr 19, 2005·AIDS Care·S Naar-KingC Arfken

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Citations

Sep 12, 2007·Journal of Pediatric Psychology·Alexandra L QuittnerMichael A Rapoff
Oct 26, 2010·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Patricia A GarvieJ Christopher Young
Oct 5, 2013·AIDS Care·Sumathi SivapalasingamRobert Holzman
Apr 27, 2017·Cadernos de saúde pública·Elisangela da Costa Lima-DellamoraThiago Botelho Azeredo
Aug 21, 2008·Journal of Developmental and Behavioral Pediatrics : JDBP·John J FarleyUNKNOWN PACTG P1042S Team
Mar 27, 2020·International Journal of Environmental Research and Public Health·Brandon ChuaKai Zhen Yap

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