Bright light therapy versus physical exercise to prevent co-morbid depression and obesity in adolescents and young adults with attention-deficit / hyperactivity disorder: study protocol for a randomized controlled trial

Trials
Jutta S MayerChristine M Freitag

Abstract

The risk for major depression and obesity is increased in adolescents and adults with attention-deficit / hyperactivity disorder (ADHD) and adolescent ADHD predicts adult depression and obesity. Non-pharmacological interventions to treat and prevent these co-morbidities are urgently needed. Bright light therapy (BLT) improves day-night rhythm and is an emerging therapy for major depression. Exercise intervention (EI) reduces obesity and improves depressive symptoms. To date, no randomized controlled trial (RCT) has been performed to establish feasibility and efficacy of these interventions targeting the prevention of co-morbid depression and obesity in ADHD. We hypothesize that the two manualized interventions in combination with mobile health-based monitoring and reinforcement will result in less depressive symptoms and obesity compared to treatment as usual in adolescents and young adults with ADHD. This trial is a prospective, pilot phase-IIa, parallel-group RCT with three arms (two add-on treatment groups [BLT, EI] and one treatment as usual [TAU] control group). The primary outcome variable is change in the Inventory of Depressive Symptomatology total score (observer-blinded assessment) between baseline and ten weeks of in...Continue Reading

Associated Clinical Trials

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Citations

Sep 21, 2018·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Maria KormanAndrew N Coogan
Oct 24, 2019·Der Nervenarzt·U W Ebner-PriemerA Meyer-Lindenberg
Jun 7, 2021·Neuroscience and Biobehavioral Reviews·Elena D KochUlrich W Ebner-Priemer
Jul 7, 2021·Experimental Neurology·Markus ReichertAndreas Meyer-Lindenberg

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Methods Mentioned

BETA
psychopharmacotherapy
pharmacotherapy

Software Mentioned

FileZilla
Health
movisensXS
movisens DataAnalyzer
LightMove

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