Bright Mn-doped carbon dots for the determination of permanganate and L-ascorbic acid by a fluorescence on-off-on strategy.

Mikrochimica Acta
Xu ChuShan Huang

Abstract

A one-pot hydrothermal synthesis of manganese-doped carbon dots (Mn-CDs) is reported for fluorescent "on-off-on" determination of Mn(VII) and L-ascorbic acid (L-AA) in aqueous solution and living cells. Mn-CDs were prepared by using sulfanilic acid, tetrakis(hydroxymethyl)phosphonium chloride, and Mn(II) chloride as precursors. Mn-CDs were characterized by several spectroscopic methods and microscopic techniques. Mn-CDs show distinctly long fluorescence lifetime (12.39 ± 0.07 ns) and high absolute fluorescence quantum yield (around 37%) with excitation and emission wavelengths of 362 and 500 nm, respectively. Mn-CDs exhibit no significant cytotoxicity to human cervical carcinoma HeLa cells and human embryonic kidney HEK-293T cells at 200 μg mL-1 level after 48 h incubation. The fluorescence of Mn-CDs at 500 nm (excited at 362 nm) is quenched efficiently by Mn(VII) and can be further recovered after the addition of L-AA, resulting in a fluorescent "on-off-on" assay for the determination of Mn(VII) and L-AA. Under optimal experimental conditions, the linear response covers the 3 to 150 μM Mn(VII) concentration range and the 3 to 140 μM L-AA concentration range. This method offers relatively low detection limits of 0.66 μM for Mn(...Continue Reading

References

Oct 8, 2004·Journal of the American Chemical Society·Xiaoyou XuWalter A Scrivens
Apr 8, 2017·ACS Applied Materials & Interfaces·Yueh-Yun YaoJia-Yaw Chang
Mar 10, 2019·Mikrochimica Acta·Meghdad PirsahebMehrdad Payandeh
Jun 11, 2018·ACS Biomaterials Science & Engineering·Zhe JiWei Gu

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Citations

Mar 7, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Tengfei WangYu Wang

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