PMID: 11933129Apr 5, 2002Paper

Brine shrimp lethality assay of Bacopa monnieri

Phytotherapy Research : PTR
Prashanth D'SouzaAmit Agarwal

Abstract

Successive petroleum ether, chloroform, ethanol and water extracts, a saponin rich fraction (SRF) and bacoside A isolated from Bacopa monnieri were tested for brine shrimp lethality. Successive ethanol extracts and SRF showed potent activity. Bacoside A showed the maximum activity with a LC(50) of 38.3 microg/mL. The results confirmed the previous reports of an anticancer effect of Bacopa monnieri and suggest bacoside A as the active constituent.

References

Mar 1, 1982·Journal of Ethnopharmacology·H K Singh, B N Dhawan

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Citations

Nov 17, 2009·Journal of Cancer Research and Clinical Oncology·Panneerselvam JananiChandrakesan Parthasarathy
Jan 20, 2010·Cell Biochemistry and Function·Panneerselvam JananiChandrakesan Parthasarathy
Nov 19, 2005·Phytochemistry·Chillara SivaramakrishnaGottumukkala V Subbaraju
Dec 11, 2008·Phytotherapy Research : PTR·G Rohini, C S Shyamala Devi

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