Bringing memory fMRI to the clinic: comparison of seven memory fMRI protocols in temporal lobe epilepsy.

Human Brain Mapping
Karren TowgoodM P Richardson

Abstract

fMRI is increasingly implemented in the clinic to assess memory function. There are multiple approaches to memory fMRI, but limited data on advantages and reliability of different methods. Here, we compared effect size, activation lateralisation, and between-sessions reliability of seven memory fMRI protocols: Hometown Walking (block design), Scene encoding (block design and event-related design), Picture encoding (block and event-related), and Word encoding (block and event-related). All protocols were performed on three occasions in 16 patients with temporal lobe epilepsy (TLE). Group T-maps showed activity bilaterally in medial temporal lobe for all protocols. Using ANOVA, there was an interaction between hemisphere and seizure-onset lateralisation (P = 0.009) and between hemisphere, protocol and seizure-onset lateralisation (P = 0.002), showing that the distribution of memory-related activity between left and right temporal lobes differed between protocols and between patients with left-onset and right-onset seizures. Using voxelwise intraclass Correlation Coefficient, between-sessions reliability was best for Hometown and Scenes (block and event). The between-sessions spatial overlap of activated voxels was also greatest f...Continue Reading

References

Jul 16, 1994·BMJ : British Medical Journal·D G Altman, J M Bland
Jul 3, 1998·Cerebral Cortex·D N KennedyV S Caviness
May 3, 2001·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·I LoubinouxF Chollet
Jun 1, 2001·The American Journal of Psychiatry·D S ManoachR L Gollub
Aug 4, 2001·The New England Journal of Medicine·S WiebeUNKNOWN Effectiveness and Efficiency of Surgery for Temporal Lobe Epilepsy Study Group
Nov 28, 2001·Neurology·H JokeitF G Woermann
Feb 6, 2004·Nature Neuroscience·Mark P RichardsonRaymond J Dolan
Mar 10, 2004·NeuroImage·Xingchang WeiLawrence P Panych
Jul 30, 2004·Epilepsia·John A Detre
Aug 27, 2004·Brain : a Journal of Neurology·Marcie L RabinJohn A Detre
Oct 2, 2004·Brain : a Journal of Neurology·Mark P RichardsonRaymond J Dolan
Feb 1, 2005·Epilepsia·Jozsef JanszkyFriedrich G Woermann
Feb 16, 2005·Epilepsy & Behavior : E&B·Veena M NarayanJohn A Detre
Jun 25, 2005·NeuroImage·Jörn Diedrichsen, Reza Shadmehr
Nov 23, 2006·IEEE Transactions on Medical Imaging·William R CrumDerek L G Hill
Mar 28, 2007·Journal of Neuroscience Methods·Marko Wilke, Karen Lidzba
Jul 20, 2007·Human Brain Mapping·Lee FriedmanSteven G Potkin
Sep 28, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·H W R PowellM J Koepp
Dec 26, 2007·Magnetic Resonance Imaging·Mohamed L Seghier
Mar 25, 2008·Epilepsy & Behavior : E&B·A HaagUNKNOWN Arbeitsgemeinschaft für Prächirurgische Epilepsiediagnostik und Operative Epilepsietherapie e.V
Jul 9, 2008·Current Opinion in Neurology·Carolina CiumasPhilippe Ryvlin
Jan 27, 2009·NeuroImage·Alejandro CaceresMitul A Mehta
Mar 24, 2009·Journal of Magnetic Resonance Imaging : JMRI·James T VoyvodicAllan H Friedman
Aug 14, 2009·Epilepsy & Behavior : E&B·Dawn Mechanic-HamiltonJohn A Detre
Feb 17, 2010·Brain : a Journal of Neurology·Silvia B BonelliJohn S Duncan
Feb 10, 2011·Nature Reviews. Neurology·Brian BellBruce Hermann

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Citations

Mar 2, 2016·Lancet Neurology·John S DuncanSebastien Ourselin
Jun 6, 2015·Epilepsia·Nicholas J BeimerSimon M Glynn
Nov 25, 2016·Epilepsia·Erwin A van VlietPaolo Federico
Jun 30, 2019·Frontiers in Neurology·Rudolf KreidenhuberStefan Rampp
Jun 2, 2020·Neurosurgery Clinics of North America·Niels Alexander FoitNeda Bernasconi
Jun 21, 2021·NeuroImage. Clinical·Anna DollJohanna Kissler

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Methods Mentioned

BETA
surgical resection

Software Mentioned

SPM8
SPSS
FSL
Word
SPM

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