Brodifacoum-contaminated synthetic marijuana: clinical and radiologic manifestations of a public health outbreak causing life-threatening coagulopathy

Emergency Radiology
Babita PanigrahiSteven P Rowe

Abstract

Synthetic marijuana is a dangerous substance due to its potency, ever-changing composition, and unpredictable side effects. Recently, brodifacoum-contaminated synthetic marijuana has led to multiple deaths and morbidity throughout the USA from severe coagulopathy associated with use of this strain of the drug (brodifacoum is a rodenticide and potent Vitamin K antagonist/anticoagulant). We describe the clinical and radiologic findings in two patients who were diagnosed with, and treated for, ingestion of this new strain of synthetic marijuana. The radiologic manifestations were most notable for hemorrhagic pyelitis/ureteritis. Both patients required hospitalization with Vitamin K supplementation. The radiologic and clinical pictures in these patients are important for radiologists to recognize in order to help guide appropriate patient management.

References

Feb 1, 1993·The American Journal of Pediatric Hematology/oncology·J BabcockB Alving
Apr 2, 2014·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Elizabeth L UnderwoodBrian N Walker
Oct 30, 2014·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·John R Senior
May 1, 2015·Addiction Science & Clinical Practice·Michael F WeaverErik W Gunderson
Sep 1, 2015·Neurology·David Z RoseW Scott Burgin
Oct 25, 2017·JAAPA : Official Journal of the American Academy of Physician Assistants·Shaina A Freund, Adrian S Banning
May 1, 2018·Proceedings·Brooke MillsCarlos E Velasco

❮ Previous
Next ❯

Citations

Dec 5, 2019·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Jason M DevgunSteven E Aks
Mar 8, 2019·The Mental Health Clinician·Azita AlipourStephen Gabrielson
Aug 28, 2020·Journal of Community Hospital Internal Medicine Perspectives·Priyanka ParajuliAlan Deckard
Dec 5, 2019·ACS Chemical Neuroscience·Adam Worob, Cody Wenthur

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Related Papers

Journal of the American Veterinary Medical Association
G B Braithwaite
JAMA : the Journal of the American Medical Association
J J Corrigan, F I Marcus
© 2022 Meta ULC. All rights reserved