PMID: 7677439Aug 1, 1995

Bronchial hyperreactivity in systemic sclerosis patients: influence of associated Sjögren's syndrome

Annals of the Rheumatic Diseases
R La CorteF Trotta

Abstract

To determine the frequency and relative risk of bronchial hyperreactivity to methacholine in systemic sclerosis patients with or without associated Sjögren's syndrome. A prospective study of 56 patients with systemic sclerosis (42 with the diffuse and 14 with the limited variant; 24 with associated Sjögren's syndrome), 57 with primary Sjögren's syndrome, and 61 healthy controls. Bronchial hyperreactivity (BH) was present in 6.5% of the healthy controls, 25% of the systemic sclerosis patients without associated Sjögren's syndrome, 42.2% of those with primary Sjögren's syndrome, and in 50% of those with systemic sclerosis with associated Sjögren's syndrome. The presence of BH did not correlate with age, disease duration, chest radiograph abnormalities, respiratory, and immunological data. The subgroup of subjects with the limited variant of systemic sclerosis more frequently had associated BH than did those with the diffuse variant of the disease; coexisting Sjögren's syndrome further increased this frequency. In agreement with previous studies, we have confirmed the high prevalence of bronchial hyperreactivity in primary Sjögren's syndrome; systemic sclerosis likewise appears to be associated with an increased frequency of bronc...Continue Reading

References

Jun 22, 2002·AJR. American Journal of Roentgenology·B PartikT H Helbich
Jan 1, 2007·Women's Health·Ibtisam Al-Hashimi
Feb 28, 2002·The American Journal of Gastroenterology·K R HerrlingerK Fellermann
Sep 7, 2016·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Andrew J Ghio
Feb 2, 2018·Clinical Rheumatology·Matthew KoslowIssahar Ben-Dov
Jun 2, 2016·European Respiratory Review : an Official Journal of the European Respiratory Society·Thomas FlamentSylvain Marchand-Adam
Nov 1, 2008·Expert Review of Clinical Immunology·Alberto Tedeschi, Riccardo Asero

Citations

Apr 1, 1978·Archives of Ophthalmology·J P GilbardJ Santamaria
Oct 1, 1975·The Journal of Allergy and Clinical Immunology·H ChaiR G Townley
Jan 1, 1991·Annals of the Rheumatic Diseases·B GudbjörnssonR Hällgren
Feb 1, 1989·The Journal of Allergy and Clinical Immunology·S P O'HickeyT H Lee
Sep 1, 1987·Annals of the Rheumatic Diseases·A M NahirY Scharf
May 1, 1986·The Journal of Allergy and Clinical Immunology·C M Smith, S D Anderson
Oct 1, 1985·Arthritis and Rheumatism·P F Kohler, M E Winter
Feb 1, 1974·Oral Surgery, Oral Medicine, and Oral Pathology·J S GreenspanR A Sylvester
Jun 28, 1971·JAMA : the Journal of the American Medical Association·G L SchallN Talal

Related Concepts

Waardenburg Syndrome
Plain X-ray
Bronchial Provocation Tests
Anterior Thoracic Region
Chest
Lobar Bronchus Structure
Methacholine
Sicca Syndrome
Bronchoconstrictor Effect
Forced Expiratory Volume Function

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