Bronchial infiltration with diffuse large B-cell lymphoma

Leukemia Research
Satoshi HaraToshiaki Hanafusa

Abstract

Non-Hodgkin's lymphoma (NHL) refers to a heterogeneous group of lymphoproliferative diseases with a diversity of clinical courses, including involvement in another organs. NHL frequently involves the thoracic structures, and particularly the mediastinum and lung parenchyma. Several clinical reports have described bronchial-associated lymphoid tissue (BALT) lymphoma as an endobronchial lesion, but endobronchial infiltration with diffuse large B-cell lymphoma is extremely rare. Here, we provide the first report of this condition confirmed by a histopathological study and the presence of an immunoglobulin heavy chain (IgH) gene rearrangement detected by a polymerase chain reaction (PCR).

References

Jan 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·M L ClearyJ Sklar

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