Abstract
The contemporary diagnosis of bronchiectasis requires CT scanning to describe specific structural lung changes. Scoring systems have been designed and validated in some specific causes of bronchiectasis to allow investigators to correlate CT changes with other indices of disease severity, to describe changes over time, with exacerbation and in response to treatment. Several scoring systems have been developed for CF including the Bhalla Score, Brody score, and the Helbich score. These scoring systems have also been applied to other causes of bronchiectasis including Primary Ciliary Dyskinesia (PCD). This assumes that the nature of structural lung disease in these conditions, as well as the rate and nature of longitudinal changes are identical to, or at least very similar to, those found in CF. This assumption has not been tested. The underlying pathophysiology of PCD is not the same as CF and may cause bronchiectasis that is radiologically similar but not necessarily the same as CF or any other cause of bronchiectasis. The development of a disease specific scoring system for structural change in cases of non-CF bronchiectasis due to any cause, would require consideration of the full range of changes seen in that condition witho...Continue Reading
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Citations
Mar 15, 2019·Pediatric Pulmonology·Israel AmiravRonly H-E Cohn
Aug 29, 2018·Multidisciplinary Respiratory Medicine·Stefano Aliberti, James D Chalmers
Jun 5, 2020·ERJ Open Research·Cristina Ardura-GarciaClaudia E Kuehni
Aug 6, 2021·ERJ Open Research·June K MarthinKim G Nielsen
Nov 18, 2021·Journal of Paediatrics and Child Health·Loraine FabriPhilip Robinson