PMID: 15235235Jul 6, 2004Paper

Bronchiolitis obliterans after allogenic bone marrow transplantation: HRCT findings

Korean Journal of Radiology : Official Journal of the Korean Radiological Society
Jung Im JungSeog Hee Park

Abstract

To evaluate the high resolution computed tomography (HRCT) findings of bronchiolitis obliterans (BO) after bone marrow transplantation (BMT). During the past three years, 11 patients were diagnosed as having BO after BMT when they developed irreversible air flow obstruction, with an FEV(1) value of less than 80% of the baseline value, without any clinical evidence of infection. All 11 patients underwent HRCT, of whom eight also underwent follow-up HRCT. The HRCT images were assessed retrospectively for the presence of decreased lung attenuation, segmental or subsegmental bronchial dilatation, diminution of peripheral vascularity, centrilobular nodules, and branching linear structure on the inspiratory images. The lobar distribution of the decreased lung attenuation and bronchial dilatation was also examined. The presence of air trapping was investigated on the expiratory images. The interval changes of the HRCT findings were evaluated in those patients who had followup images. Abnormal HRCT findings were present in all cases; the most common abnormalities were decreased lung attenuation (n=11), subsegmental bronchial dilatation (n=6), diminution of peripheral vascularity (n=6), centrilobular nodules or branching linear structur...Continue Reading

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Citations

Feb 8, 2006·Current Opinion in Oncology·Arkadiusz Z Dudek, Hemchandra Mahaseth
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Mar 13, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Ryota HamadaShuichi Matsuda

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