PMID: 10081638Mar 19, 1999Paper

Bronchiolitis obliterans organizing pneumonia associated with Pneumocystis carinii infection in a liver transplant patient receiving tacrolimus

Clinical Transplantation
R KleindienstW Vogel

Abstract

We report on a case of bronchiolitis obliterans organizing pneumonia (BOOP) associated with Pneumocystis carinii pneumonia (PCP) after liver transplantation and tacrolimus based immunosuppression. Radiologically, bilateral diffuse interstitial shadowing and patchy alveolar infiltrates developed after switching the patient from cyclosporin A to tacrolimus for persistent rejection. Bronchoalveolar lavage (BAL) fluid showed inflammatory cells but no pathogenic organisms. Open lung biopsy revealed BOOP with granulomatous PCP. Thus, even in the case of negative BAL the possibility of an atypical P. carinii infection has to be considered for differential diagnosis of pneumonia in immunocompromised patients after organ transplantation. The combination of BOOP with PCP after liver transplantation and tacrolimus medication has not been reported previously.

References

Mar 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L R HirschhornT S Dermody
Sep 1, 1995·Thorax·U CostabelH Teschler
Jan 26, 1995·The New England Journal of Medicine·J JosephM D Frye
Jan 1, 1995·Thorax·U OzçelikN Kiper
Jun 1, 1994·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Y S LeoR D Meyer
Oct 1, 1993·Thorax·N M FoleyR F Miller
Nov 1, 1995·The European Respiratory Journal·J F Cordier
Sep 1, 1996·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·R VerberckmoesY Vanrenterghem

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