Bronchioloalveolar carcinoma: a review.

Clinical Lung Cancer
Dan J RazDavid M Jablons

Abstract

Bronchioloalveolar carcinoma (BAC) is classified as a subset of lung adenocarcinoma but has a distinct clinical presentation, tumor biology, response to therapy, and prognosis compared with other subtypes of non-small-cell lung carcinoma (NSCLC). Bronchioloalveolar carcinoma disproportionately affects women, never-smokers, and Asians and is characterized by growth along alveolar septae without evidence of stromal, vascular, or pleural invasion. Although pure BAC accounts for approximately 4% of lung cancers, tumors with histologically mixed BAC and adenocarcinoma account for > 20% of all NSCLCs, and the incidence of BAC might be increasing. Bronchioloalveolar carcinoma histology is most commonly found in small lesions identified incidentally on chest radiographs or computed tomography scans and might represent a precursor lesion to invasive adenocarcinoma. As with other subsets of NSCLC, surgical resection is the only potentially curative treatment. Patients with unresectable BAC are more likely to respond to the epidermal growth factor receptor tyrosine kinase inhibitors gefitinib and erlotinib than patients with other subtypes of NSCLC. Stage for stage, patients with BAC have a higher rate of long-term survival but might have...Continue Reading

References

Feb 29, 1992·BMJ : British Medical Journal·A Morabia, E L Wynder
Nov 1, 1991·Cancer·O Auerbach, L Garfinkel
Dec 1, 1994·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A M PeterschmittE M Brambilla
Jun 1, 1997·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·M W BeckmannH G Bender
Nov 15, 1997·Journal of the National Cancer Institute·M J ThunC W Heath
Aug 7, 1998·AJR. American Journal of Roentgenology·S L AquinoP Halford
Oct 3, 1999·The Journal of Thoracic and Cardiovascular Surgery·K OkuboD J Mathisen
Dec 10, 1999·AJR. American Journal of Roentgenology·M AkiraT Johkoh
Apr 6, 2000·The Annals of Thoracic Surgery·K SuzukiY Nishiwaki
Jun 29, 2001·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·K KodamaT Nakayama
Jul 19, 2001·The British Journal of Radiology·J I JungB G Choi
Jul 21, 2001·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·A CarrettaP Zannini
Jan 11, 2002·The New England Journal of Medicine·Joan H SchillerUNKNOWN Eastern Cooperative Oncology Group
May 9, 2002·Radiology·Edith M MaromEdward F Patz
Aug 23, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Cecelia S YapJohannes Czernin
Nov 26, 2002·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Laura E Heyneman, Edward F Patz
May 20, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·József FurákAdám Balogh
Jul 11, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Fabrice BarlesiPascal Thomas
Oct 22, 2003·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Da-Li TianHou-Wen Li
Dec 4, 2003·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Michele GaetaStefano Cascinu
Dec 11, 2003·The Journal of Thoracic and Cardiovascular Surgery·Peter F RobertsJohn R Benfield
Mar 17, 2004·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·M WislezJ Cadranel
May 29, 2004·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Reda S SaadJan F Silverman
Jun 26, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·David R GandaraWilbur A Franklin
Jun 26, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Giorgio V ScagliottiFred R Hirsch
Jul 13, 2004·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·William L ReadRamaswamy Govindan
Jul 27, 2004·American Journal of Clinical Pathology·Kristen A Atkins
Aug 27, 2004·Proceedings of the National Academy of Sciences of the United States of America·William PaoHarold Varmus
Oct 1, 2004·Nature·Philip StephensMichael R Stratton

❮ Previous
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Citations

Apr 19, 2011·Seminars in Respiratory and Critical Care Medicine·Ping Yang
Apr 18, 2013·Journal of Cardiothoracic Surgery·Zhenfa ZhangChangli Wang
May 25, 2013·The Permanente Journal·H Nicole TranArthur L Klatsky
Mar 20, 2014·BMC Research Notes·Nicolle M Linnerth-PetrikSarah K Wootton
Jul 1, 2010·Case Reports in Medicine·Carolina Lamas ConstantinoRomulo Varella de Oliveira
Jul 21, 2012·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Paige M BracciJohn K Wiencke
Dec 6, 2008·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Fred R HirschMauro Papotti
Apr 28, 2010·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Takeshi HanagiriKosei Yasumoto
Jan 22, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·William D TravisDavid Yankelewitz
Oct 30, 2010·Asian Journal of Surgery·Souichi OkaKosei Yasumoto
Oct 12, 2011·Surgical Oncology Clinics of North America·Zhen Fan, Richard Schraeder
Mar 18, 2011·American Journal of Clinical Pathology·William SterlacciMichael Fiegl
Mar 1, 2011·Molecular and Cellular Endocrinology·Yasuhiro MikiHironobu Sasano
May 5, 2009·Experimental and Molecular Pathology·Teresa W-M FanDonald M Miller
Apr 6, 2007·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Dan J RazDavid M Jablons
Feb 27, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Katsuo UsudaTsutomu Sakuma
Oct 22, 2016·Thoracic Cancer·Bing-Sheng SunChang-Li Wang
Aug 7, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Wen-Cheng ZhangChang-Li Wang
May 31, 2007·Current Opinion in Pulmonary Medicine·Dan J RazDavid M Jablons
Sep 3, 2011·Southern Medical Journal·Grace X MaJamil I Toubbeh
Jul 18, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Annette E MaxwellRoshan Bastani
Oct 28, 2015·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Claire H KimZuo-Feng Zhang
Apr 4, 2021·International Journal of Molecular Sciences·Linoy MehazriUri Nir
Jul 10, 2007·Archives of Pathology & Laboratory Medicine·Samuel A Yousem, Mary Beth Beasley
Jan 31, 2022·Theoretical Population Biology·Adam S Bryant, Maxim O Lavrentovich

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