PMID: 9543299May 16, 1998Paper

Bronchoalveolar lavage cell analysis in a child with chronic lipid pneumonia

The European Respiratory Journal
F MidullaR Ronchetti

Abstract

In an asymptomatic 4 yr old child with radiographic evidence of parenchymal lung disease, bronchoalveolar lavage (BAL) yielded the diagnosis of chronic lipid pneumonia caused by chronic aspiration of mineral oil given as a laxative. BAL analysis showed a marked reduction in the total number of alveolar macrophages; almost 70% of these cells contained intracytoplasmic lipid vacuoles. It also disclosed lymphocytic (cytotoxic/suppressor) alveolitis. A high percentage of lymphocytes expressed antigen markers of activation (human leucocyte antigen (HLA)-DR), CD54 and CD25). BAL analysis 18 months after mineral oil intake revealed that lymphocytes bearing antigen markers of activation had markedly decreased whereas alveolar macrophages (normal and lipid-laden) had increased. A subsequent whole lung BAL was considered unnecessarily invasive in this otherwise healthy child.

Citations

Aug 24, 2010·Orphanet Journal of Rare Diseases·Annick ClementHarriet Corvol
Sep 6, 2003·Advances in Therapy·Claudio TerzanoNicoletta De Luca
Sep 6, 2005·Revue de pneumologie clinique·Dominique Israel-Biet, Claire Danel
Mar 14, 2009·Pediatric Pulmonology·Selma M A SiasThereza Quirico-Santos
May 2, 2015·American Journal of Respiratory and Critical Care Medicine·Albert FaroUNKNOWN American Thoracic Society Ad Hoc Committee on Flexible Airway Endoscopy in Children
Dec 28, 2010·Respiratory Medicine·Edson MarchioriBruno Hochhegger
Aug 16, 2016·Respirology Case Reports·Takamasa HottaTakeshi Isobe
Aug 5, 2016·Journal of Occupational Health·Chenghong HanMeibian Zhang
Dec 16, 2017·The European Respiratory Journal·Ernst EberFabio Midulla
Mar 28, 2017·ERJ Open Research·Yvette A HaymanAlyn H Morice
Aug 2, 2017·Expert Opinion on Drug Safety·Blanca Serrano-Falcón, Enrique Rey
Mar 1, 2001·Paediatrics & Child Health·M Weinstein
Dec 15, 2016·Case Reports in Pulmonology·Franck RahaghiBasheer Tashtoush
Aug 11, 2018·Respirology Case Reports·Diana MaranguMarco Zampoli
Oct 13, 2009·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Selma Maria de Azevedo SiasThereza Quirico-Santos
Sep 12, 2012·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Maria Cristina Ribeiro dos Santos SimõesAdyléia Aparecida Dalbo Contrera Toro
Sep 18, 2020·The Clinical Respiratory Journal·Lianhan ShangUNKNOWN for CAP-China Network

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