PMID: 8965361May 1, 1996Paper

Bronchoscopic brachytherapy: development of bronchoscopic ultrasonography and brachytherapy for early stage lung cancer of hilar type

Nihon rinsho. Japanese journal of clinical medicine
R Ono

Abstract

We have recently developed bronchoscopic brachytherapy as a new modality for treating tracheal and bronchial malignancies, and have assessed the feasibility of bronchoscopic ultrasonic diagnosis and bronchoscopic brachytherapy for tracheal and bronchial malignant diseases, using a combination of videobronchoscope, an ultrasonic probe and a high-dose-rate Microselectron. Between September 1992 and December 1994, 34 patients having a total of 34 lesions of the trachea and bronchus received bronchoscopic brachytherapy at the National Cancer Center Hospital. In all 34 of these cases lung cancer was histologically confirmed by biopsy before treatment, although these cancer lesions were roentgenographically occult. Of the 34 patients who received bronchoscopic brachytherapy, 33 patients showed complete response to this therapy. Although 4 patients died of other diseases, the 3-year survival rate was 88.6%. The results of our study show that in such cases bronchoscopic brachytherapy yields a high rate of therapeutic response.

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.