Brown tumor due to primary hyperparathyroidism resulting in acute paraparesis: Case report and literature review

Surgical Neurology International
Ahmed Taha Elsayed ShaabanAbdulnasser Alyafai

Abstract

Brown tumor (Osteoclastoma) is a rare benign, focal, lytic bone lesion most commonly attributed to a parathyroid adenoma; it occurs in approximately 5% of patients with primary hyperparathyroidism, and 13% of patients with secondary hyperparathyroidism. Most tumors are located in the mandible, pelvis, ribs, and large bones; only rarely is it found in the axial spine. A 37-year-old male with primary hyperparathyroidism presented with an MR-documented T4 and T5 brown tumor (Osteitis Fibrosa Cystica) resulting in an acute paraparesis. The patient successfully underwent excisional biopsy of an expansile, enhancing, bony destructive lesion at the T4-5 level. Subsequently, he required subtotal excision of a left upper parathyroid tumor. Patient with primary hyperparathyroidism may acutely present with paraparesis attributed to brown tumors of the spine warranting emergent operative decompression.

References

Jun 10, 2009·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·S Noman ZaheerNikitas J Vrodos
Nov 22, 2011·World Neurosurgery·Kyle M FargenGregory J Velat
Dec 24, 2011·Annales d'endocrinologie·Cécile GrégoirePierre Weinmann
Dec 12, 2012·Indian Journal of Endocrinology and Metabolism·Ekram UllahNavneet Redhu
Nov 21, 2015·Journal of Korean Neurosurgical Society·Erkin SonmezAysen Terzi

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BETA
biopsy
X-ray

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