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Brucella suppress innate immunity by down-regulating STING expression in macrophages

bioRxiv

Jan 2, 2020

Mike KhanJudith A Smith

Abstract

Brucellosis, caused by Brucella bacteria species, remains the most prevalent zoonotic disease worldwide. Brucella establish chronic infections within host macrophages despite triggering cytosolic innate immune sensors, including Stimulator of Interferon Genes (STING), which potentially ...read more

Mentioned in this Paper

ERN1 protein, human
Zoonoses
RNA, Messenger
IFNG gene
MIR24-2 wt Allele
Protein Expression
TMEM173
TMEM173 gene
MicroRNAs
Study
8
Paper Details
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Brucella suppress innate immunity by down-regulating STING expression in macrophages

bioRxiv

Jan 2, 2020

Mike KhanJudith A Smith

DOI: 10.1101/2019.12.31.891051

Abstract

Brucellosis, caused by Brucella bacteria species, remains the most prevalent zoonotic disease worldwide. Brucella establish chronic infections within host macrophages despite triggering cytosolic innate immune sensors, including Stimulator of Interferon Genes (STING), which potentially ...read more

Mentioned in this Paper

ERN1 protein, human
Zoonoses
RNA, Messenger
IFNG gene
MIR24-2 wt Allele
Protein Expression
TMEM173
TMEM173 gene
MicroRNAs
Study
8

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