Brunner's gland adenoma: a rare cause of vomiting

Acta Paediatrica
Nafiye UrganciAsiye Nuhoğlu


Upper gastrointestinal system adenoma is generally seen amongst elderly patients and quite rarely seen during the childhood. A 14-y-old female patient was referred to our hospital with complaints of vomiting and abdominal pain. She had been followed up for 6 y with the diagnosis of familial intermittent fever and chronic renal failure due to amyloidosis. Endoscopic examination of the upper gastrointestinal system revealed mild hyperaemia in the corpus and antrum, and a polyp of 0.5x0.5 cm with an ulcerated and pedunculated top in the bulbus. Brunner's gland adenoma was diagnosed by the histopathological examination of the lesion following polypectomy. Brunner's gland adenoma is usually asymptomatic; however, it may reveal clinical findings such as obstruction, bleeding or intussusception, especially in uraemic patients. Thus, we would like to emphasize that, in patients with chronic renal failure and acute onset vomiting and abdominal pain, Brunner's gland adenoma should be considered in the differential diagnosis.


Jan 1, 1979·Scandinavian Journal of Gastroenterology·O CrivelliG Verme
May 1, 1996·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·I RantalaK Ala-Kaila
Oct 21, 1998·Journal of Pediatric Gastroenterology and Nutrition·M P Sande-Lemos AzcueP M Sherman
Sep 9, 1999·Journal of Clinical Gastroenterology·O AdeonigbagbeM Washington

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May 25, 2006·Acta Paediatrica·Mukadder Ayse SelimogluMukaddes Esrefoglu

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