PMID: 12045780Jun 5, 2002Paper

Brunner's gland hamartoma: a rare cause of gastrointestinal bleeding -- case report and review of the literature

Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
David R StolpmanDeepak V Gopal


An unusual cause of upper gastrointestinal bleeding is described in a previously healthy 45-year-old man who was admitted to hospital with weakness and fatigue, and had experienced an episode of melena two days before admission. His medical and surgical history was unremarkable. Upon admission to hospital, he showed evidence of iron-deficiency anemia, with a hemoglobin concentration of 61 g/L (normal range 135 to 175 g/L), a mean corpuscular volume of 73 fL (normal range 85.0 to 95.0 fL) and a ferritin concentration of 1.0 microg/L (normal range in males 15 to 400 microg/L). Upper gastrointestinal endoscopy revealed a 3.5 cm ulcerated submucosal mass in the third portion of the duodenum, for which mucosal biopsies were nondiagnostic. A subsequent endoscopic ultrasound revealed a 2.7 x 4.0 cm hyperechoic, cystic, submucosal tumour in the third portion of the duodenum. Endoscopic ultrasound-guided fine needle aspiration revealed no malignant cells. The patient eventually underwent a resection of the third portion of his duodenum. Surgical pathology revealed that this tumour was a Brunner's gland hamartoma, 4.5 cm in its greatest dimension.


Aug 25, 2006·AJR. American Journal of Roentgenology·Nandini D PatelLeslie H Sobin
May 14, 2008·Southern Medical Journal·Ravi R KurellaRichard Harty
Jul 27, 2010·Journal of Computer Assisted Tomography·Saebeom HurByung Ihn Choi
Apr 30, 2010·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·E Reichenbach-KlinkeP Sterk
Mar 17, 2017·Case Reports in Surgery·Nicola C FrenkelJeroen Hagendoorn
Jan 13, 2012·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Janna Berendina HouwersNikolaas Hofstee
Jul 27, 2006·Pancreas·Vilma Salvatori ChappuisHanifa Bouzourene
Mar 3, 2006·Diagnostic Cytopathology·Ricardo H BardalesMichael W Stanley
Jul 2, 2010·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jongmee LeeKee-Taek Jang
Mar 1, 2006·Gastroentérologie Clinique Et Biologique·Pierre-Alexandre JustFrédérique Capron

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