Brush-evoked allodynia predicts outcome of spinal cord stimulation in complex regional pain syndrome type 1

European Journal of Pain : EJP
Frank van EijsCatharina G Faber

Abstract

Spinal cord stimulation (SCS) has proven to be an effective however an invasive and relatively expensive treatment of chronic Complex Regional Pain Syndrome type 1(CRPS-1). Furthermore, in one third of CRPS-1 patients, SCS treatment fails to give significant pain relief and 32-38% of treated patients experience complications. The aim of the current study was to develop effective prognostic factors for prediction of successful outcome of SCS. The study population consisted of 36 chronic CRPS patients enrolled in a randomized controlled trial of SCS efficacy. We analyzed various prognostic factors in the group of patients treated with SCS and compared baseline values of possible predictors of outcome in the successfully treated and the not successfully treated group. Success was defined as Patient Global Perceived Impression of Change score of at least "much improved" and pain reduction of at least 2.5 on a visual-analogue scale (VAS score 0-10). Univariate analyses showed that patient age, duration of the disease, localization of the disease, intensity of the pain, and the presence of mechanical hypoesthesia did not predict SCS success. The mean and maximum value of brush-evoked allodynia proved to be statistically significant p...Continue Reading

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Mar 15, 2012·Current Pain and Headache Reports·I Elias VeiziJeffrey W Janata
Jan 10, 2013·Current Pain and Headache Reports·Chitra RamasubbuKayode Williams
Feb 15, 2012·Neuromodulation : Journal of the International Neuromodulation Society·Frank van EijsMaarten van Kleef
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