"Bubble-like" lung metastases in osteosarcoma patients

European Journal of Radiology
Antonio BriccoliMarco Alberghini

Abstract

Cavitation of pulmonary metastases have been reported by several authors either as a spontaneous phenomenon or as a consequence of chemotherapy. We present two cases, with this type of image in follow-up, and 20-45 months after the end of treatment. This was the first sign of pulmonary metastases. Two patients with osteogenic sarcoma developed radiological evidence of pulmonary "bubble-like" cavitation several years following completion of chemotherapy. In one patient the "bubble-like" cavitation transformed into a solid nodule. Both patients had surgical resections of all pulmonary lesions, and histology confirmed presence of viable osteosarcoma metastases. The two cases suggest that onset of "bubble-like" cavitation in lung parenchyma of osteosarcoma patients may be the first sign of pulmonary metastases.

References

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Jan 1, 1996·European Radiology·C J HeroldD Fleischmann
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Aug 10, 2005·Respiration; International Review of Thoracic Diseases·Necla SongurAhmet Uçaner

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Citations

Oct 17, 2015·European Journal of Radiology·Federica CiccareseDaniel Vanel
Apr 14, 2021·Pediatric Radiology·Michal ScolnikAnat Ilivitzki

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