Bullous lesions in Bazex syndrome and successful treatment with oral psoralen phototherapy

The Australasian Journal of Dermatology
D GillJ Kelly

Abstract

A 59-year-old man presented with a psoriasiform dermatitis with associated bullae and destructive nail dystrophy of the hands and feet. He had lost 10 kg weight over 6 months and a mass in the neck was noted. He was provisionally diagnosed with Bazex syndrome (acrokeratosis paraneoplastica) and subsequent investigations revealed a squamous cell carcinoma in the right piriform fossa. His skin lesions were treated with oral psoralen and ultraviolet A phototherapy and this cleared the cutaneous changes, but the nail changes have persisted at 18 months follow up.

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Citations

Aug 20, 2010·Head and Neck Pathology·Alan Roger Santos-SilvaMarcio Ajudarte Lopes
May 18, 2005·Clinics in Dermatology·Stephen P Stone, Lucinda S Buescher
Nov 15, 2011·Rheumatic Diseases Clinics of North America·Anjali ShahR Samuel Hopkins
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Nov 14, 2006·Journal of the American Academy of Dermatology·Paul-Gunther SatorFriedrich Gschnait
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Mar 9, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·F RäßlerP Elsner
May 31, 2018·JAAPA : Official Journal of the American Academy of Physician Assistants·Megan L AdelmanAmit Agrawal
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Jun 27, 2006·Actas dermo-sifiliográficas·Miguel CabanillasJaime Toribio

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