PMID: 9175398Apr 1, 1997Paper

Bullous pemphigoid in an infant: a case report and literature review

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
W WisuthsarewongK Kulthanan

Abstract

Bullous pemphigoid is an autoimmune bullous disease that is rare in children and infants. It seems indistinguishable from the disease in adults although mucous membrane, palms and soles involvement appear more commonly in childhood bullous pemphigoid. There is no association with malignancy. The most reliable diagnostic criterias are the linear deposition of IgG and C3 along the basement membrane zone and the presence of circulating IgG antibasement membrane zone antibodies. The literature of bullous pemphigoid is reviewed and a case of a 7-month-old girl with typical clinical manifestations and immunofluorescence studies is reported. She responded very well to a high dose of systemic corticosteroid. The disease can be spontaneously resolved and the prognosis for children is good in most cases.

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete
E KerstingE B Bröcker
Journal of the American Academy of Dermatology
C W YungA L Lorincz
Journal of the American Academy of Dermatology
Y TamadaK Owaribe
© 2021 Meta ULC. All rights reserved