Burden of bacterial meningitis in India: Preliminary data from a hospital based sentinel surveillance network

PloS One
Yuvaraj JayaramanHospital Based Sentinel Surveillance of Bacterial Meningitis (HBSSBM) Network Team

Abstract

Worldwide, acute bacterial meningitis is a major cause of high morbidity and mortality among under five children, particularly in settings where vaccination for H. influenzae type b, S. pneumoniae and N. meningitidis is yet to be introduced in the national immunization programs. Estimation of disease burden of bacterial meningitis associated with these pathogens can guide the policy makers to consider inclusion of these newer vaccines in the immunization programs. A network of hospital based sentinel surveillance was established to generate baseline data on the burden of bacterial meningitis among children aged less than 5 years in India and to provide a platform for impact assessment following introduction of the Pentavalent and Pneumococcal Conjugate Vaccines (PCV). During surveillance carried out in select hospitals across India in 2012-2013, information regarding demographics, immunization history, clinical history, treatment details and laboratory investigations viz. CSF biochemistry, culture, latex agglutination and PCR was collected from children aged 1 to 59 months admitted with suspected bacterial meningitis. A total of 3104 suspected meningitis cases were enrolled from 19,670 children admitted with fever at the survei...Continue Reading

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Citations

Jul 25, 2020·Infectious Diseases and Therapy·Ashok Kumar DuttaSripriya Sathyanarayanan
Oct 2, 2020·Tropical Doctor·Sumayya Abdul KalamO C Abraham
Jun 5, 2020·Journal of Clinical Imaging Science·Devkant LakheraRohitash Sharma
Jul 9, 2020·International Journal of Environmental Research and Public Health·Neha SharmaKhalid M Khan
Jan 30, 2021·Indian Journal of Pediatrics·Nabaneeta Dash, Jitendra Kumar Sahu
Mar 19, 2019·Indian Journal of Medical Microbiology·Anand Manoharan, Ranjith Jayaraman
Sep 12, 2021·Neurology India·Miguel Bertelli RamosEberval Gadelha Figueiredo

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Methods Mentioned

BETA
PCR

Software Mentioned

SPSS

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