Burden of focal cryoablation versus brachytherapy versus active surveillance in the treatment of very low-risk prostate cancer: a preliminary head-to-head comprehensive assessment.

European Journal of Cancer Care
M A de CerqueiraL O Reis

Abstract

Focal cryoablation (FC), brachytherapy (B) and active surveillance (AS) were offered to patients diagnosed with very low-risk prostate cancer (VLRPC) in an equal access protocol. Comprehensive validated self-report questionnaires accessed patients' erectile (IIEF-5) and voiding (IPSS) functions, Beck scales measured anxiety (BAI), hopelessness (BHS) and depression (BDI), SF-36 reflected patients' quality of life added to the emotional thermometers including five visual analogue scales (distress, anxiety, depression, anger and need for help). Kruskal-Wallis or ANOVA tests and Spearman's correlations were obtained among groups and studied variables. Thirty patients were included, median follow-up 18 months (15-21). Those on AS (n = 11) were older, presented higher hopelessness (BHS) and lower general health perceptions (SF-36) scores than patients opting for FC (n = 10) and B (n = 9), P = 0.0014, P = 0.0268 and P = 0.0168 respectively. Patients on B had higher IPSS scores compared to those under FC and AC, P = 0.0223. For all 30 included patients, Spearman's correlation (rs ) was very strong between BHS and general health perceptions (rs  = -0.800, P < 0.0001), and weak/moderate between age and BHS (rs  = 0.405, P = 0.026) and ag...Continue Reading

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Citations

May 1, 2015·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Leonardo de Oliveira Reis, H Ballentine Carter
Apr 26, 2019·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Leonardo O ReisFernando J Bianco
Jul 3, 2019·World Journal of Urology·Michael A CerqueiraLeonardo Oliveira Reis
Feb 15, 2020·International Urology and Nephrology·Walker Wendell LaranjaLeonardo Oliveira Reis

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